Leveraging semiconducting polymer nanoparticles for combination cancer immunotherapy

J Wu, K Pu - Advanced Materials, 2024 - Wiley Online Library
Cancer immunotherapy has become a promising method for cancer treatment, bringing
hope to advanced cancer patients. However, immune‐related adverse events caused by …

[HTML][HTML] Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …

Renal Clearable Nanodots‐Engineered Erythrocytes with Enhanced Circulation and Tumor Accumulation for Photothermal Therapy of Hepatocellular Carcinoma

Q Li, M Jin, Z Ding, D Luo, S Wang, X Bao, Z Liu, W Wei - Small, 2024 - Wiley Online Library
Living cell‐mediated nanodelivery system is considered a promising candidate for targeted
antitumor therapy; however, their use is restricted by the adverse interactions between …

Reducing Cholesterol Level in Live Macrophages Improves Delivery Performance by Enhancing Blood Shear Stress Adaptation

M Zhang, J Li, N Ji, Q Bao, N Sun, H Rong, X Peng… - Nano Letters, 2023 - ACS Publications
In recent years, live-cell-based drug delivery systems have gained considerable attention.
However, shear stress, which accompanies blood flow, may cause cell death and weaken …

Immunogenicity of Extracellular Vesicles

Y Xia, J Zhang, G Liu, J Wolfram - Advanced Materials, 2024 - Wiley Online Library
Extracellular vesicles (EVs) are promising next‐generation therapeutics and drug delivery
systems due to demonstrated safety and efficacy in preclinical models and early‐stage …

Harnessing Engineered Extracellular Vesicles from Mesenchymal Stem Cells as Therapeutic Scaffolds for Bone‐Related Diseases

T Yu, J Wang, Y Zhou, C Ma, R Bai… - Advanced Functional …, 2024 - Wiley Online Library
Mesenchymal stem cells (MSCs) play a crucial role in maintaining bone homeostasis and
are extensively explored for cell therapy in various bone‐related diseases. In addition to …

Advances in biomimetic nanomaterial delivery systems: harnessing nature's inspiration for targeted drug delivery

W Kang, Z Xu, H Lu, S Liu, J Li, C Ding… - Journal of Materials …, 2024 - pubs.rsc.org
The properties of nanomaterials make them promising and advantageous for use in drug
delivery systems, but challenges arise from the immune system's recognition of exogenous …

[HTML][HTML] The combined characteristics of cholesterol metabolism and the immune microenvironment may serve as valuable biomarkers for both the prognosis and …

W Bai - Heliyon, 2023 - cell.com
Background Hepatocellular carcinoma (HCC) being a complex disease, commonly exhibits
multifaceted presentations, rendering its treatment challenging and necessitating specific …

Chlorin e6 and BLZ945 Based Self‐Assembly for Photodynamic Immunotherapy through Immunogenic Tumor Induction and Tumor Associated Macrophage Depletion

CY Huang, LP Zhao, XN Rao, RR Zheng… - Advanced …, 2024 - Wiley Online Library
Immunotherapeutic effect is restricted by the non‐immunogenic tumor phenotype and
immunosuppression behaviors of tumor associated macrophages (TAMs). In this work, a …