An escalating" epidemic” of diseases like Alzheimer's has not yet been met by effective
symptomatic treatments or preventative strategies. Among a few current prescription drugs …

Ethnopharmacological relevance A widely used traditional prescription, Yi-Gan San (YGS) is
a remedy for neurodegenerative disorders. The formulation consists of seven Chinese …

Dementia is a progressive neurodegenerative disorder with cognitive dysfunction, and is
often complicated by behavioral and psychological symptoms of dementia (BPSD) including …

Yokukansan (YKS), a traditional Japanese medicine, is composed of seven kinds of dried
herbs. It is widely prescribed in clinical situation for treating psychiatric disorders such as …

Geissoschizine methyl ether (GM) in Uncaria hook, a galenical constituent of yokukansan is
thought to be one of active components in the psychotropic effect of yokukansan, a …

The deposition of amyloid β protein (Aβ) is a consistent pathological hallmark of Alzheimer's
disease (AD) brains. Therefore, inhibition of Aβ aggregation in the brain is an attractive …

Aim Yokukansan (YKS), a traditional herbal medicine, has been used to treat behavioral and
psychological symptoms of dementia (BPSD). The present study is the first double‐blind …

Abstract Alzheimer's disease (AD), which is the most major cause of dementia, is a
progressive neurodegenerative disease that affects cognitive functions. Even though the …

Japanese traditional herbal medicine (Kampo) has its origins in traditional Chinese
medicine (TCM). It was introduced to Japan in the middle of the sixth century and has …

Management of the behavioural and psychological symptoms of dementia remains a
challenge worldwide. Herbal medicines may play a role in the development of new …