Recent advances in the synthesis and utility of thiazoline and its derivatives

S Kumar, A Arora, S Sapra, R Kumar, BK Singh… - RSC …, 2024 - pubs.rsc.org
Thiazolines and their derivatives hold significant importance in the field of medicinal
chemistry due to their promising potential as pharmaceutical agents. These molecular …

A green synthesis, DFT calculations, and molecular docking study of some new indeno [2, 1-b] quinoxalines containing thiazole moiety

AM Abdallah, SM Gomha, MEA Zaki… - Journal of Molecular …, 2023 - Elsevier
A series of new indenoquinoxaline-thiazole hybrids were synthesized by combining
indenoquinoxaline thiosemicarbazone with appropriate hydrazonoyl chlorides or α-halo …

Thione derivatives as medicinally important compounds

A Das, MW Ashraf, BK Banik - ChemistrySelect, 2021 - Wiley Online Library
Like nitrogen‐containing heterocycles, sulfur‐containing heterocyclic compounds also have
a lot of significant applications. These sulfur heterocycles are mainly used as a core for the …

Synthesis, Characterization, and Biological Evaluation of Some Novel Pyrazolo[5,1-b]thiazole Derivatives as Potential Antimicrobial and Anticancer Agents

A Alsayari, AB Muhsinah, YI Asiri, FA Al-Aizari… - Molecules, 2021 - mdpi.com
The pharmacological activities of thiazole and pyrazole moieties as antimicrobial and
anticancer agents have been thoroughly described in many literature reviews. In this study …

Cd (II) complexes derived from thiazoline, hydrazide and carbodithioate ligands: synthesis, crystal structures and electrochemical sensing of uric acid

S Jaiswal, SK Pandey, J Prajapati… - Applied …, 2023 - Wiley Online Library
Three novel Cd (II) metal complexes 1–3 have been synthesized with different derivatives of
thiazoline, hydrazide and carbodithioate. These metal complexes are abbreviated as [Cd …

Novel thiazoline–coumarin hybrid compounds containing sugar moieties: synthesis, biological evaluation and molecular docking study as antiproliferative agents

VN Toan, ND Thanh - New Journal of Chemistry, 2021 - pubs.rsc.org
A new series of 2, 3-thiazoline–coumarin hybrid compounds that contained D-glucose and D-
galactose moieties (4a–g) were synthesized and their cytotoxic activity was evaluated …

Convenient synthesis and anticancer evaluation of novel pyrazolyl‐thiophene, thieno [3, 2‐b] pyridine, pyrazolo [3, 4‐d] thieno [3, 2‐b] pyridine and pyrano [2, 3‐d] …

GS Masaret - Journal of Heterocyclic Chemistry, 2021 - Wiley Online Library
The newly synthesized 3‐(3‐amino‐5‐(phenylamino)‐4‐(phenylcarbamoyl) thiophen‐2‐yl)‐
3‐oxopropanoate was utilized as a precursor for the synthesis of pyrazolyl‐thiophene …

Chemoselective synthesis, X-ray structure study, Hirshfeld surface analysis, antitumor, and antimicrobial activities of new Thiophene and Thiazole derivatives

AB Muhsinah, MM Alharbi, NA Kheder… - Journal of Molecular …, 2024 - Elsevier
A base-controlled chemoselective reaction of 1-phenylbutane-1, 3‑dione with PhNCS and 1-
chloropropan-2-one is described. Thiophene derivative 5 is obtained from the reaction in …

New N-Adducts of Thiadiazole and Thiazoline with Levoglucosenone and Evaluation of Their Significant Cytotoxic (Anti-Cancer) Activity

T Poplawski, G Galita, J Sarnik, A Macieja, R Bielski… - Cancers, 2024 - mdpi.com
Simple Summary The anticancer effects reported in several heterocyclic derivatives of
thiadiazole and thiazoline prompted us to construct functionalized new carbohydrate …

Design, synthesis, X-ray analysis, and biological screening of new oxime and enaminone thiazoline-2-thione derivatives

YI Asiri, AB Muhsinah, A Alsayari, HA Ghabbour… - Journal of Molecular …, 2021 - Elsevier
An urgent need exists to develop antimicrobial and anticancer drugs that are safer and less
prone to the development of resistance. To this end, a series of 12 new thiazoline-2-thione …