New technologies for analysis of extracellular vesicles
Extracellular vesicles (EVs) are diverse, nanoscale membrane vesicles actively released by
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
cells. Similar-sized vesicles can be further classified (eg, exosomes, microvesicles) based …
Lung cancer: current therapies and new targeted treatments
Lung cancer is the most frequent cause of cancer-related deaths worldwide. Every year, 1· 8
million people are diagnosed with lung cancer, and 1· 6 million people die as a result of the …
million people are diagnosed with lung cancer, and 1· 6 million people die as a result of the …
Gefitinib versus vinorelbine plus cisplatin as adjuvant treatment for stage II–IIIA (N1–N2) EGFR-mutant NSCLC (ADJUVANT/CTONG1104): a randomised, open-label …
WZ Zhong, Q Wang, WM Mao, ST Xu, L Wu… - The Lancet …, 2018 - thelancet.com
Background Cisplatin-based adjuvant chemotherapy is the standard of care for patients with
resected stage II–IIIA non-small-cell lung cancer (NSCLC). RADIANT and SELECT trial data …
resected stage II–IIIA non-small-cell lung cancer (NSCLC). RADIANT and SELECT trial data …
Radiomics signature: a potential biomarker for the prediction of disease-free survival in early-stage (I or II) non—small cell lung cancer
Purpose To develop a radiomics signature to estimate disease-free survival (DFS) in
patients with early-stage (stage I–II) non–small cell lung cancer (NSCLC) and assess its …
patients with early-stage (stage I–II) non–small cell lung cancer (NSCLC) and assess its …
[HTML][HTML] The IASLC lung cancer staging project: proposals for the revision of the M descriptors in the forthcoming eighth edition of the TNM classification of lung cancer
WEE Eberhardt, A Mitchell, J Crowley, H Kondo… - Journal of thoracic …, 2015 - Elsevier
Introduction The aim of this study is to analyze all metastatic (M) categories of the current
tumor, node, and metastasis (TNM) classification of lung cancer with the objective of …
tumor, node, and metastasis (TNM) classification of lung cancer with the objective of …
[HTML][HTML] 2nd ESMO Consensus Conference in Lung Cancer: locally advanced stage III non-small-cell lung cancer
WEE Eberhardt, D De Ruysscher, W Weder… - Annals of …, 2015 - Elsevier
To complement the existing treatment guidelines for all tumour types, ESMO organises
consensus conferences to focus on specific issues in each type of tumour. The 2nd ESMO …
consensus conferences to focus on specific issues in each type of tumour. The 2nd ESMO …
Long-term follow-up results of the DANTE trial, a randomized study of lung cancer screening with spiral computed tomography
Rationale: Screening for lung cancer with low-dose spiral computed tomography (LDCT)
has been shown to reduce lung cancer mortality by 20% compared with screening with …
has been shown to reduce lung cancer mortality by 20% compared with screening with …
[HTML][HTML] Exosomal proteins as diagnostic biomarkers in lung cancer
B Sandfeld-Paulsen, KR Jakobsen, R Bæk… - Journal of Thoracic …, 2016 - Elsevier
Introduction Exosomes have been suggested as promising biomarkers in NSCLC because
they contain proteins from their originating cells and are readily available in plasma. In this …
they contain proteins from their originating cells and are readily available in plasma. In this …
Integrating multiple machine learning methods to construct glutamine metabolism-related signatures in lung adenocarcinoma
Background Glutamine metabolism (GM) is known to play a critical role in cancer
development, including in lung adenocarcinoma (LUAD), although the exact contribution of …
development, including in lung adenocarcinoma (LUAD), although the exact contribution of …
Prediction of disease-free survival by the PET/CT radiomic signature in non-small cell lung cancer patients undergoing surgery
M Kirienko, L Cozzi, L Antunovic, L Lozza… - European journal of …, 2018 - Springer
Purpose Radiomic features derived from the texture analysis of different imaging modalities
e show promise in lesion characterisation, response prediction, and prognostication in lung …
e show promise in lesion characterisation, response prediction, and prognostication in lung …