Recent Advances in Reprogramming Strategy of Tumor Microenvironment for Rejuvenating Photosensitizers‐Mediated Photodynamic Therapy

Q Yu, X Li, J Wang, L Guo, L Huang, W Gao - Small, 2024 - Wiley Online Library
Photodynamic therapy (PDT) has recently been considered a potential tumor therapy due to
its time‐space specificity and non‐invasive advantages. PDT can not only directly kill tumor …

[HTML][HTML] Glioblastoma metabolism: insights and therapeutic strategies

C Bernhard, D Reita, S Martin, N Entz-Werle… - International Journal of …, 2023 - mdpi.com
Tumor metabolism is emerging as a potential target for cancer therapies. This new approach
holds particular promise for the treatment of glioblastoma, a highly lethal brain tumor that is …

Engineering Cell Membrane‐Cloaked Catalysts as Multifaceted Artificial Peroxisomes for Biomedical Applications

D Yang, Y Tang, B Zhu, H Pang, X Rong… - Advanced …, 2023 - Wiley Online Library
Artificial peroxisomes (APEXs) or peroxisome mimics have caught a lot of attention in
nanomedicine and biomaterial science in the last decade, which have great potential in …

Biocompatible snowman-like tumor-targeting dimer nanoparticles for improved delivery efficiency and enhanced anti-tumor therapy

C Ye, X Yan, X Dai, R Chen, Q Li, S Xu, Q Jiang… - Chemical Engineering …, 2023 - Elsevier
Chemotherapy is indispensable for the systematic treatment of aggressive malignancies,
such as pancreatic ductal adenocarcinoma (PDAC), while delivery vehicles are essential for …

A three-stage eccDNA based molecular profiling significantly improves the identification, prognosis assessment and recurrence prediction accuracy in patients with …

Z Li, B Wang, H Liang, Y Li, Z Zhang, L Han - Cancer Letters, 2023 - Elsevier
Glioblastoma (GBM) progression is influenced by intratumoral heterogeneity. Emerging
evidence has emphasized the pivotal role of extrachromosomal circular DNA (eccDNA) in …

Reusable and near-infrared light-activated Zinc (II) metalated porphyrin with synergetic PDT/PTT for eradicating bacterial pneumonia

X Duan, J Li, S Huang, A Li, Y Zhang, Y Xue… - Chemical Engineering …, 2023 - Elsevier
Phototherapy is an alternative treatment for combating bacterial infections without inducing
antibiotic resistance. We synthesized a reusable and NIR-responsive zinc-metalated …

Current advances on nanomaterials interfering with lactate metabolism for tumor therapy

Q Cheng, XL Shi, QL Li, L Wang, Z Wang - Advanced Science, 2024 - Wiley Online Library
Increasing numbers of studies have shown that tumor cells prefer fermentative glycolysis
over oxidative phosphorylation to provide a vast amount of energy for fast proliferation even …

[HTML][HTML] Evaluation of cell membrane-derived nanoparticles as therapeutic carriers for pancreatic ductal adenocarcinoma using an in vitro tumour stroma model

C Tapeinos, G Torrieri, S Wang, JP Martins… - Journal of Controlled …, 2023 - Elsevier
Here, we fabricated nanoparticles made solely from the membrane of cells found in the
pancreatic tumour's microenvironment (TME), like the human MiaPaCa-2 cells and M2 …

Revolutionizing neurocare: biomimetic nanodelivery via cell membranes

J Liao, L Gong, Q Xu, J Wang, Y Yang… - Advanced …, 2024 - Wiley Online Library
Brain disorders represent a significant challenge in medical science due to the formidable
blood–brain barrier (BBB), which severely limits the penetration of conventional …

[HTML][HTML] Diagnostic and therapeutic approaches for glioblastoma and neuroblastoma cancers using chlorotoxin nanoparticles

T Boltman, M Meyer, O Ekpo - Cancers, 2023 - mdpi.com
Simple Summary Glioblastoma multiforme (GB) and neuroblastomas (NBs) are nervous
system cancers that are difficult to diagnosis and treat. Chlorotoxin (CTX), is a peptide …