Innate and adaptive immunity during SARS-CoV-2 infection: biomolecular cellular markers and mechanisms
The coronavirus 2019 (COVID-19) pandemic was caused by a positive sense single-
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
stranded RNA (ssRNA) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
High titers and low fucosylation of early human anti–SARS-CoV-2 IgG promote inflammation by alveolar macrophages
Patients diagnosed with coronavirus disease 2019 (COVID-19) become critically ill primarily
around the time of activation of the adaptive immune response. Here, we provide evidence …
around the time of activation of the adaptive immune response. Here, we provide evidence …
[HTML][HTML] COVID-19 and HIV-associated immune reconstitution inflammatory syndrome: emergence of pathogen-specific immune responses adding fuel to the fire
N Seddiki, M French - Frontiers in Immunology, 2021 - frontiersin.org
Both coronavirus disease 2019 (COVID-19) and mycobacterial immune reconstitution
inflammatory syndrome (IRIS) in patients with HIV-1 infection result from immunopathology …
inflammatory syndrome (IRIS) in patients with HIV-1 infection result from immunopathology …
Nano selenium-enriched probiotic Lactobacillus enhances alum adjuvanticity and promotes antigen-specific systemic and mucosal immunity
R Liu, W Sun, T Sun, W Zhang, Y Nan, Z Zhang… - Frontiers in …, 2023 - frontiersin.org
Nano selenium-enriched probiotics have been identified to improve immune responses,
such as alleviating inflammation, antioxidant function, treatment of tumors, anticancer …
such as alleviating inflammation, antioxidant function, treatment of tumors, anticancer …
An anti-LpqH human monoclonal antibody from an asymptomatic individual mediates protection against Mycobacterium tuberculosis
Tuberculosis (TB) is an airborne disease caused by Mycobacterium tuberculosis (Mtb).
Whilst a functional role for humoral immunity in Mtb protection remains poorly defined …
Whilst a functional role for humoral immunity in Mtb protection remains poorly defined …
Computer vision analysis of rheumatoid arthritis synovium reveals lymphocytic inflammation is associated with immunoglobulin skewing in blood
D Frezza, E DiCarlo, C Hale, D Ramirez… - Arthritis & …, 2023 - Wiley Online Library
Objective We sought to develop computer vision methods to quantify aggregates of cells in
synovial tissue and compare these to clinical and gene expression parameters. Methods We …
synovial tissue and compare these to clinical and gene expression parameters. Methods We …
Physiological and pathological inflammation induced by antibodies and pentraxins
Macrophages play a key role in induction of inflammatory responses. These inflammatory
responses are mostly considered to be instigated by activation of pattern recognition …
responses are mostly considered to be instigated by activation of pattern recognition …
Rituximab induced cytokine release with high serum IP-10 (CXCL10) concentrations is associated with infusion reactions
JE Moore, PC Bloom, CC Chu, JE Bruno, CA Herne… - Leukemia Research, 2023 - Elsevier
Monoclonal antibody induced infusion reactions (IRs) can be serious and even fatal. We
used clinical data and blood samples from 37 treatment naïve patients with chronic …
used clinical data and blood samples from 37 treatment naïve patients with chronic …
Evaluation and validation of the prognostic value of anti-MDA5 IgG subclasses in dermatomyositis-associated interstitial lung disease
YT Xu, YM Zhang, HX Yang, LF Ye, F Chen, X Lu… - …, 2023 - academic.oup.com
Objective To investigate the association between the anti-melanoma differentiation
associated gene 5 (MDA5) IgG subclasses and prognosis of patients with dermatomyositis …
associated gene 5 (MDA5) IgG subclasses and prognosis of patients with dermatomyositis …
[HTML][HTML] IgA2 immune complexes selectively promote inflammation by human CD103+ dendritic cells
While immunoglobulin A (IgA) is well known for its neutralizing and anti-inflammatory
function, it is becoming increasingly clear that IgA can also induce human inflammatory …
function, it is becoming increasingly clear that IgA can also induce human inflammatory …