Power to mechanical power to minimize ventilator-induced lung injury?

PL Silva, L Ball, PRM Rocco, P Pelosi - Intensive care medicine …, 2019 - Springer
Mechanical ventilation is a life-supportive therapy, but can also promote damage to
pulmonary structures, such as epithelial and endothelial cells and the extracellular matrix, in …

Intelligent decision support with machine learning for efficient management of mechanical ventilation in the intensive care unit–A critical overview

CI Ossai, N Wickramasinghe - International Journal of Medical Informatics, 2021 - Elsevier
Abstract Background Effective management of Mechanical Ventilation (MV) is vital for
reducing morbidity, mortality, and cost of healthcare. Objective This study aims to synthesize …

Which component of mechanical power is most important in causing VILI?

JJ Marini, PRM Rocco - Critical Care, 2020 - Springer
Repeated applications of tidal energy inflict lung damage (VILI) when stress and strain
exceed the limits of tissue tolerance. Inflation work and energy are the products of pressure …

Lung injury is induced by abrupt increase in respiratory rate but prevented by recruitment maneuver in mild acute respiratory distress syndrome in rats

PH Xavier, ACF Fonseca, LA Gonçalves… - …, 2023 - pubs.asahq.org
Background Gradually changing respiratory rate (RR) during time to reduce ventilation-
induced lung injury has not been investigated. The authors hypothesized that gradual …

Utility of driving pressure and mechanical power to guide protective ventilator settings in two cohorts of adult and pediatric patients with acute respiratory distress …

S Saffaran, A Das, JG Laffey, JG Hardman… - Critical care …, 2020 - journals.lww.com
Objectives: Mechanical power and driving pressure have been proposed as indicators, and
possibly drivers, of ventilator-induced lung injury. We tested the utility of these different …

Feasibility and safety of ultra-low tidal volume ventilation without extracorporeal circulation in moderately severe and severe ARDS patients

JC Richard, S Marque, A Gros, M Muller, G Prat… - Intensive Care …, 2019 - Springer
Purpose Mechanical ventilation with ultra-low tidal volume (VT) during ARDS may reduce
alveolar strain, driving pressure and hence ventilator-induced lung injury, with the main …

Management of intraoperative mechanical ventilation to prevent postoperative complications after general anesthesia: a narrative review

A Fogagnolo, F Montanaro, L Al-Husinat… - Journal of clinical …, 2021 - mdpi.com
Mechanical ventilation (MV) is still necessary in many surgical procedures; nonetheless,
intraoperative MV is not free from harmful effects. Protective ventilation strategies, which …

Elastic power but not driving power is the key promoter of ventilator-induced lung injury in experimental acute respiratory distress syndrome

PRM Rocco, PL Silva, CS Samary, MK Hayat Syed… - Critical Care, 2020 - Springer
Background We dissected total power into its primary components to resolve its relative
contributions to tissue damage (VILI). We hypothesized that driving power or elastic …

Mechanical power is associated with weaning outcome in critically ill mechanically ventilated patients

Y Yan, Y Xie, X Chen, Y Sun, Z Du, Y Wang, X Li - Scientific Reports, 2022 - nature.com
Several single-center studies have evaluated the predictive performance of mechanical
power (MP) on weaning outcomes in prolonged invasive mechanical ventilation (IMV) …

Elastic power of mechanical ventilation in morbid obesity and severe hypoxemia

MKH Syed, J Selickman, MD Evans, D Dries… - Respiratory …, 2021 - rc.rcjournal.com
BACKGROUND: To minimize ventilator-induced lung injury, the primary clinical focus is
currently expanding from measuring static indices of the individual tidal cycle (eg, plateau …