Oxidative damage is a common and early feature of Alzheimer's disease, Parkinson's
disease, amyotrophic lateral sclerosis (ALS), and other neurodegenerative disorders. Dr …

Abstract Amyotrophic Lateral Sclerosis (ALS) is a devastating heterogeneous disease with
still no convincing therapy. To identify the most strategically significant hallmarks for …

In a variety of tissues, cumulative oxidative stress, disrupted mitochondrial respiration, and
mitochondrial damage promote aging, cell death, and ultimately, functional failure and …

Peroxynitrite is formed in biological systems when nitric oxide and superoxide rapidly
interact at near equimolar ratio. Peroxynitrite, though not a free radical by chemical nature, is …

Nitric oxide (NO) has been established as an important messenger molecule in various
steps of brain physiology, from development to synaptic plasticity, learning and memory …

Amyotrophic lateral sclerosis (ALS) is characterized by a progressive loss of large motor
neurons in the brain and spinal cord. Amyloid precursor protein (APP), the transmembrane …

Effective therapies are needed for amyotrophic lateral sclerosis (ALS), a debilitating and
fatal motor neuron disease. Cell and animal models of ALS are begsinning to reveal …

Objective: The objective of this retrospective review was to examine the impact that adding
photobiomodulation therapy (PBMt) to rehabilitation therapy had on the pathology of …

To investigate cytokine/chemokine changes in amyotrophic lateral sclerosis (ALS), we
simultaneously measured 16 cytokine/chemokines (interleukin [IL]-1β, IL-2, IL-4, IL-5, IL-6, IL …

Both transforming growth factor‐β1 (TGF‐β1) and nitric oxide synthase‐2 (NOS‐2) are
upregulated under various neuropathological states. Evidence suggests that TGF‐β1 can …