Oxidative stress in immune-mediated motoneuron destruction
L Xu, YS Guo, YL Liu, SY Wu, C Yang, DX Wu, HR Wu… - Brain research, 2009 - Elsevier
Experimental autoimmune gray matter disease (EAGMD) is a model of both upper and lower
motor neuron degeneration. EAGMD and amyotrophic lateral sclerosis (ALS) possess …
motor neuron degeneration. EAGMD and amyotrophic lateral sclerosis (ALS) possess …
Angeli's salt and spinal motor neuron injury
AJ Väänänen, R Liebkind, E Kankuri, P Liesi… - Free radical …, 2004 - Taylor & Francis
Nitroxyl anion or its conjugate acid (NO-/HNO) and nitric oxide (NO) may both have pro-
oxidative and cytotoxic properties. Superoxide dismutase (SOD) enzyme has been shown to …
oxidative and cytotoxic properties. Superoxide dismutase (SOD) enzyme has been shown to …
Cerebrospinal fluid nitrite and malondialdehyde levels in patients with motor neuron disease
R Shukla, M Rajani, MK Barthwal… - International journal …, 2003 - Taylor & Francis
Nitric oxide (NO) mediated oxidative damage may be involved in the pathogenesis of
neuronal degeneration in motor neuron disease (MND). The present study was undertaken …
neuronal degeneration in motor neuron disease (MND). The present study was undertaken …
Expression of inducible nitric oxide synthase and elevation of tyrosine nitration of a 32-kilodalton cellular protein in brain capillary endothelial cells from rats infected …
A Jinno-Oue, SG Wilt, C Hanson, NV Dugger… - Journal of …, 2003 - Am Soc Microbiol
ABSTRACT PVC-211 murine leukemia virus (MuLV) is a neuropathogenic variant of Friend
MuLV (F-MuLV) which causes a rapidly progressive spongiform neurodegenerative disease …
MuLV (F-MuLV) which causes a rapidly progressive spongiform neurodegenerative disease …
Fluorescence assay for monitoring Zn-deficient superoxide dismutase in vitro
DV Martyshkin, SB Mirov, YX Zhuang, JP Crow… - … Acta Part A: Molecular …, 2003 - Elsevier
A method has been developed for selective detection of the zinc-deficient form of Cu, Zn
superoxide dismutase (SOD1) in vitro. Zinc-deficient SOD1 mutants have been implicated in …
superoxide dismutase (SOD1) in vitro. Zinc-deficient SOD1 mutants have been implicated in …
[PDF][PDF] Update on the pathological roles of prostaglandin E
H Nango, K Tsuruta, H Miyagishi, Y Aono… - 2023 - translationalneurodegeneration …
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease
characterized by selective degeneration of upper and lower motor neurons. The …
characterized by selective degeneration of upper and lower motor neurons. The …
Superoxide dismutase, oxidative stress, and ALS
JS Beckman, AG Estevez - NEUROLOGICAL DISEASE AND …, 2006 - api.taylorfrancis.com
The discovery of mutations to the antioxidant enzyme copper, zinc superoxide dismutase
(SOD) in 1993 led to still unfulfilled hopes that new treatments for amyotrophic lateral …
(SOD) in 1993 led to still unfulfilled hopes that new treatments for amyotrophic lateral …
Nitric oxide affects the phosphorylation state of microtubule-associated protein 2 (MAP-2) and neurofilament: an immunocytochemical study in the brain of rats and …
F Rothe, H Possel, G Wolf - Nitric Oxide, 2002 - Elsevier
Alterations in function and specific cellular location of cytoskeletal elements are
characterized by changes in their phosphorylation state. On this background we studied …
characterized by changes in their phosphorylation state. On this background we studied …
Proapoptotic Nitric Oxide Production in Amyloid β Protein-Treated Cerebral Microvascular Endothelial Cells
C Kimura, M Oike, M Watanabe, Y Ito - Microcirculation, 2007 - Taylor & Francis
Objective: The objective of this study was to investigate the effects of amyloid β protein (Aβ)
on cerebral microvascular endothelium, and their possible involvement in Aβ-induced …
on cerebral microvascular endothelium, and their possible involvement in Aβ-induced …
In situ temporospatial characterization of the glial response to prion infection
AV Michael, JJ Greenlee, TA Harm… - Veterinary …, 2020 - journals.sagepub.com
Mammalian transmissible spongiform encephalopathies (TSEs) display marked activation of
astrocytes and microglia that precedes neuronal loss. Investigation of clinical parallels …
astrocytes and microglia that precedes neuronal loss. Investigation of clinical parallels …