Nitric oxide NO is an atypical neurotransmitter and is formed from L-arginine by the enzyme
nitric oxide synthase (NOS), which is of three types, namely neuronal NOS (nNOS) …

研究脂多糖(LPS) 诱导的炎症反应对运动神经元的损伤作用及其机制. 采用SD
乳鼠脊髓器官型培养, 分为单纯培养液组和不同浓度LPS 组, 应用免疫组化, 酶活性测定 …

Amyotrophic lateral sclerosis 8 (ALS8) is a late-onset slow-progressing form of motor
neurone disease caused by a missense mutation replacing cytosine with thymine in the …

Introduction: There are extensive people exposures to paraquat (PQ) herbicide resulting in
human health hazards. Aim of the Work: To compare the beneficial neuroprotective effects of …

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease with unknown
pathogenic causes. The identification of mutated genes in familial forms of ALS has lead to …

Publisher Summary This chapter discusses the role of excitotoxicity and oxidative stress in
the pathogenesis of amyotrophic lateral sclerosis (ALS). Although recent data offer strong …

Resumen La Esclerosis Lateral Amiotrófica (ELA) es una enfermedad neurodegenerativa
fatal, progresiva que afecta las motoneuronas superiores e inferiores del sistema nervioso …

Nitric oxide (nitrogen monoxide; NO) is a simple molecular specie that has diverse, yet
versatile biological functions. As a biological emissary, NO and its redox derivatives …

Although Amyotrophic Lateral Sclerosis (ALS) is a neurodegenerative disease characterized
by motor neuron death, recent studies now implicate the non-neuronal environment as a …