Pathogenicity islands in bacterial pathogenesis

H Schmidt, M Hensel - Clinical microbiology reviews, 2004 - Am Soc Microbiol
In this review, we focus on a group of mobile genetic elements designated pathogenicity
islands (PAI). These elements play a pivotal role in the virulence of bacterial pathogens of …

The Accessory Genome of Pseudomonas aeruginosa

VL Kung, EA Ozer, AR Hauser - Microbiology and molecular …, 2010 - Am Soc Microbiol
Pseudomonas aeruginosa strains exhibit significant variability in pathogenicity and
ecological flexibility. Such interstrain differences reflect the dynamic nature of the P …

Complete genome sequence and comparative analysis of the metabolically versatile Pseudomonas putida KT2440

KE Nelson, C Weinel, IT Paulsen… - Environmental …, 2002 - Wiley Online Library
Pseudomonas putida is a metabolically versatile saprophytic soil bacterium that has been
certified as a biosafety host for the cloning of foreign genes. The bacterium also has …

[HTML][HTML] Pseudomonas aeruginosa genomic structure and diversity

J Klockgether, N Cramer, L Wiehlmann… - Frontiers in …, 2011 - frontiersin.org
The Pseudomonas aeruginosa genome (G+ C content 65–67%, size 5.5–7 Mbp) is made up
of a single circular chromosome and a variable number of plasmids. Sequencing of …

Modulation of Pseudomonas aeruginosa gene expression by host microflora through interspecies communication

K Duan, C Dammel, J Stein, H Rabin… - Molecular …, 2003 - Wiley Online Library
The change in gene expression patterns in response to host environments is a prerequisite
for bacterial infection. Bacterial diseases often occur as an outcome of the complex …

The broad host range pathogen Pseudomonas aeruginosa strain PA14 carries two pathogenicity islands harboring plant and animal virulence genes

J He, RL Baldini, E Déziel, M Saucier… - Proceedings of the …, 2004 - National Acad Sciences
The ubiquitous bacterium Pseudomonas aeruginosa is the quintessential opportunistic
pathogen. Certain isolates infect a broad range of host organisms, from plants to humans …

Conservation of genome content and virulence determinants among clinical and environmental isolates of Pseudomonas aeruginosa

MC Wolfgang, BR Kulasekara… - Proceedings of the …, 2003 - National Acad Sciences
Pseudomonas aeruginosa is a ubiquitous environmental bacterium capable of causing a
variety of life-threatening human infections. The genetic basis for preferential infection of …

Newly introduced genomic prophage islands are critical determinants of in vivo competitiveness in the Liverpool Epidemic Strain of Pseudomonas aeruginosa

C Winstanley, MGI Langille, JL Fothergill… - Genome …, 2009 - genome.cshlp.org
Pseudomonas aeruginosa isolates have a highly conserved core genome representing up
to 90% of the total genomic sequence with additional variable accessory genes, many of …

Depression and sexual dysfunction

DS Baldwin - British medical bulletin, 2001 - academic.oup.com
Adequate sexual expression is an essential part of many human relationships, and may
enhance quality of life and provide a sense of physical, psychological and social well-being …

Can laboratory reference strains mirror 'real-world'pathogenesis?

CA Fux, M Shirtliff, P Stoodley, JW Costerton - Trends in microbiology, 2005 - cell.com
The extraordinary plasticity of bacterial genomes raises concerns about the adequacy of
laboratory-adapted reference strains for the study of 'real world'pathogenesis. Some …