Some evidence suggests that caffeine, theophylline, and theobromine, as natural
methylxanthines (MTXs), possess anti-cancer effects. We systematically reviewed the animal …

Platinum-based chemotherapy failure represents a significant challenge in the management
of ovarian cancer (OC) and contributes to disease recurrence and poor prognosis. Recent …

This work aims to apply catalytic processes to promote the conversion of caffeine into
valuable dimethylxanthines via N‐demethylation reaction. Thus, we seek to evaluate the …

Background In many cocoa intervention studies, health outcomes are related to cocoa
components without taking into account the bioavailability of the main bioactive components …

This comprehensive review elucidates the potential health benefits of theobromine, the
principal psychopharmacological compound abundant in cocoa beans and various other …

Energy drinks are widely used and very popular. They are touted as “harmless” energy
boosters for use in professional, recreational and domestic settings. They are typically high …

BACKGROUND The development of functional foods is receiving increased recognition as a
result of the general interest in healthy diets as part of a healthier lifestyle. This project …

The functionalization of the skeletal systems of heterocycles represents a significant goal for
the development of new compounds. The heterocyclic molecule xanthine (3, 7-dihydro …

High-flavonoid cocoa consumption has been associated with beneficial properties.
However, there are scarce data concerning the effects of maternal cocoa intake on dams …

Cocoa currently faces differentiation processes toward niches of specialty products, leading
to greater competitiveness for producers who must compete with products differentiated by …