Sjögren's syndrome (SS) is a chronic autoimmune disease with the pathological hallmark of
lymphoplasmacytic infiltration of exocrine glands-more specifically salivary and lacrimal …

Salivary glands are involved in saliva secretion that ensures proper oral health. Aquaporins
are expressed in salivary glands and play a major role in saliva secretion. This review will …

The stomach is an important digestive organ with various biological functions. However,
because of the complexity of its cellular and glandular composition, its precise cellular …

Aquaporin 5 (AQP5) plays an important role in the salivary gland function. The mRNA and
protein for AQP5 are expressed in the acini from embryonic days E13-16 and E17-18 …

Abstract Background Primary Sjögren's syndrome (SS) is a lymphoproliferative disease with
a chronic autoimmune disorder characterized by mononuclear cell (MNC) infiltration of …

Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by lymphocytic
infiltration of salivary and lacrimal glands resulting in diminished production of saliva and …

Volume changes deviating from original cell volume represent a major challenge for cellular
homeostasis. Cell volume may be altered either by variations in the external osmolarity or by …

Salivary glands produce a bicarbonate-rich fluid containing digestive and protective proteins
and other components to be delivered into the gastrointestinal tract. Its function is under strict …

Several ion channels and transporters regulate fluid secretion in salivary and lacrimal
glands. In salivary glands, the major anion channel involved in fluid secretion is the calcium …

Ionizing radiation (IR) can cause damage to the structure and function of salivary glands.
Our research group independently synthesized the ROS scavenger, HL-003. The aim of this …