[HTML][HTML] An overview of tramadol and its usage in pain management and future perspective

M Subedi, S Bajaj, MS Kumar, YC Mayur - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Patients with chronic non-malignant pain report impairment of physical and social life along
with psychological state affecting their overall quality of life. The purpose of managing pain …

The role of the autonomic nervous system in cardiac arrhythmias: the neuro-cardiac axis, more foe than friend?

AA Manolis, TA Manolis, EJ Apostolopoulos… - Trends in cardiovascular …, 2021 - Elsevier
The autonomic nervous system (ANS) with its two limbs, the sympathetic (SNS) and
parasympathetic nervous system (PSNS), plays a critical role in the modulation of cardiac …

[HTML][HTML] COVID-19 infection unmasking Brugada syndrome

D Chang, M Saleh, Y Garcia-Bengo, E Choi… - HeartRhythm Case …, 2020 - Elsevier
First described in the 1990s, the Brugada syndrome initially characterized unexplained
sudden cardiac death in healthy Southeast Asian men. 1 Mutations in the cardiac sodium …

Using a smartwatch electrocardiogram to detect abnormalities associated with sudden cardiac arrest in young adults

M Nasarre, M Strik, F Daniel Ramirez, S Buliard… - EP …, 2022 - academic.oup.com
Abstract Aims Smartwatch electrocardiograms (ECGs) could facilitate the detection of
sudden cardiac arrest (SCA)-associated abnormalities. We evaluated the feasibility of using …

[HTML][HTML] Case report: State-of-the-art risk-modifying treatment of sudden cardiac death in an asymptomatic patient with a mutation in the SCN5A gene and a review of …

P Brlek, ES Pavelić, J Mešić, K Vrdoljak… - Frontiers in …, 2023 - frontiersin.org
Brugada syndrome is a rare hereditary disorder characterized by distinct ECG findings,
complex genetics, and a high risk of sudden cardiac death. Recognition of the syndrome is …

Brugada syndrome

H Korlipara, G Korlipara, S Pentyala - Acta Cardiologica, 2021 - Taylor & Francis
Brugada syndrome (BrS) is an inherited cardiac arrhythmia syndrome that causes a
heightened risk for ventricular tachyarrhythmias and sudden cardiac death. BrS is …

The influence of sex on cardiac physiology and cardiovascular diseases

Y Zhang, B Liu, R Zhao, S Zhang, X Yu, Y Li - Journal of cardiovascular …, 2020 - Springer
Cardiovascular disease (CVD) is the leading cause of death world-wide. Most of treatment
strategies were based on studies conducted on male patients. Studies have shown that …

[HTML][HTML] iPSC-cardiomyocyte models of Brugada syndrome—achievements, challenges and future perspectives

A Nijak, J Saenen, AJ Labro, D Schepers… - International journal of …, 2021 - mdpi.com
Brugada syndrome (BrS) is an inherited cardiac arrhythmia that predisposes to ventricular
fibrillation and sudden cardiac death. It originates from oligogenic alterations that affect …

[HTML][HTML] Noncoding RNAs and Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes in Cardiac Arrhythmic Brugada Syndrome

B Theisen, A Holtz, V Rajagopalan - Cells, 2023 - mdpi.com
Hundreds of thousands of people die each year as a result of sudden cardiac death, and
many are due to heart rhythm disorders. One of the major causes of these arrhythmic events …

Maternotoxicity and fetotoxicity in Rattus norvegicus albinus exposed to tramadol during the late phase of pregnancy

MF Akhtar, S Younas, A Saleem… - Birth Defects …, 2021 - Wiley Online Library
Objectives Tramadol, an atypical opioid, is clinically efficacious in treating moderate to
severe pain. The aim of current study was to find out the toxicological effects of tramadol …