Advanced glycation end products (AGEs), formed through the nonenzymatic reaction of
reducing sugars with the side-chain amino groups of lysine or arginine of proteins, followed …

Chronic obstructive pulmonary disease (COPD) patients frequently suffer from multiple
comorbidities, resulting in poor outcomes for these patients. Diabetes is observed at a …

Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality
worldwide. COPD heterogeneity has hampered progress in developing pharmacotherapies …

Chronic obstructive pulmonary disease (COPD) is a common heterogeneous respiratory
disease which is characterized by persistent and incompletely reversible airflow limitation …

Summary Background Alpha-1 Antitrypsin (AAT) deficiency (AATD), the most common
genetic cause of emphysema presents with unexplained phenotypic heterogeneity in …

Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease caused by an
aberrant repair of injured alveolar epithelial cells. The maintenance of the alveolar …

Clinical studies indicate that patients infected with SARS-CoV-2 develop hyperinflammation,
which correlates with increased mortality. The SARS-CoV-2/COVID-19-dependent …

Rationale: Quantitative interstitial abnormalities (QIAs) are early measures of lung injury
automatically detected on chest computed tomography scans. QIAs are associated with …

Systemic juvenile idiopathic arthritis (sJIA) and its complication, macrophage activation
syndrome (sJIA-MAS), are rare but sometimes very serious or even critical diseases of …

Purpose: The purpose of this study was to train and validate machine learning models for
predicting rapid decline of forced expiratory volume in 1 s (FEV1) in individuals with a …