Sophora flavescens Ait.: Traditional usage, phytochemistry and pharmacology of an important traditional Chinese medicine

X He, J Fang, L Huang, J Wang, X Huang - Journal of ethnopharmacology, 2015 - Elsevier
Abstract Ethnopharmacological relevance Sophora flavescens (Fabaceae), also known as
Kushen (Chinese: 苦参), has been an important species in Chinese medicine since the Qin …

Research advances on anticancer activities of matrine and its derivatives: An updated overview

H ur Rashid, Y Xu, Y Muhammad, L Wang… - European journal of …, 2019 - Elsevier
Cancer is the second leading cause of mortality, only overcome by cardiovascular diseases,
and has caused more than 8.7 million deaths in 2015 all over the world. This figure is …

Traditional Chinese herbal medicine as a source of molecules with antiviral activity

T Li, T Peng - Antiviral research, 2013 - Elsevier
Traditional Chinese herbal medicine (TCHM) is widely used in the prevention and treatment
of viral infectious diseases. However, the operative mechanisms of TCHM remain largely …

Sophora alopecuroides L.: An ethnopharmacological, phytochemical, and pharmacological review

R Wang, X Deng, Q Gao, X Wu, L Han, X Gao… - Journal of …, 2020 - Elsevier
Ethnopharmacological relevance Sophora alopecuroides L., which is called Kudouzi in
China, is a medicinal plant distributed in Western and Central Asia, especially in China, and …

Plant alkaloids: Structures and bioactive properties

EP Gutiérrez-Grijalva, LX López-Martínez… - Plant-derived bioactives …, 2020 - Springer
Alkaloids are nitrogen-containing natural products found in bacteria, fungi, animals, and
plants with complex and diverse structures. The widespread distribution of alkaloids along …

Chemical diversity, biological activities and Traditional uses of and important Chinese herb Sophora

P Sun, W Zhao, Q Wang, L Chen, K Sun, Z Zhan… - Phytomedicine, 2022 - Elsevier
Abstract Background Sophora flavescens Aiton (SF), also known as Kushen (Chinese: 苦参),
has been an important species in Chinese medicine since the Qin and Han dynasties. It is …

Quinolizidine-type alkaloids: chemodiversity, occurrence, and bioactivity

W Cely-Veloza, MJ Kato, E Coy-Barrera - ACS omega, 2023 - ACS Publications
Quinolizidine alkaloids (QAs) are nitrogen-containing compounds produced naturally as
specialized metabolites distributed in plants and animals (eg, frogs, sponges). The present …

Matrine-Type Alkaloids from the Roots of Sophora flavescens and Their Antiviral Activities against the Hepatitis B Virus

YB Zhang, D Luo, L Yang, W Cheng, LJ He… - Journal of natural …, 2018 - ACS Publications
Eight new matrine-type alkaloids, flavesines G–J (1–4), alopecurine B (5), 7, 11-dehydro-
oxymatrine (6), 10-oxy-5, 6-dehydromatrine (7), and 10-oxysophoridine (8), along with nine …

Antiviral Matrine-Type Alkaloids from the Rhizomes of Sophora tonkinensis

QM Pan, YH Li, J Hua, FP Huang… - Journal of natural …, 2015 - ACS Publications
Three new matrine-type alkaloids,(+)-5α-hydroxyoxysophocarpine (1),(−)-12β-
hydroxyoxysophocarpine (2), and (+)-5α-hydroxylemannine (3), along with 14 known …

Simultaneous extraction and purification of alkaloids from Sophora flavescens Ait. by microwave-assisted aqueous two-phase extraction with ethanol/ammonia sulfate …

W Zhang, D Zhu, H Fan, X Liu, Q Wan, X Wu… - Separation and …, 2015 - Elsevier
A rapid and effective method of integrating extraction and purification for alkaloids from
Sophora flavescens Ait. was developed by microwave-assisted aqueous two-phase …