Systems metabolic engineering of microorganisms for food and cosmetics production
The demand for sustainable and environmentally friendly sources of foods and cosmetics is
increasing owing to concerns about the rapid growth of the global population and climate …
increasing owing to concerns about the rapid growth of the global population and climate …
Synthetic biology of extremophiles: a new wave of biomanufacturing
JW Ye, YN Lin, XQ Yi, ZX Yu, X Liu, GQ Chen - Trends in Biotechnology, 2023 - cell.com
Microbial biomanufacturing, powered by the advances of synthetic biology, has attracted
growing interest for the production of diverse products. In contrast to conventional microbes …
growing interest for the production of diverse products. In contrast to conventional microbes …
Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors
Cellular processes are carried out by many genes, and their study and optimization requires
multiple levers by which they can be independently controlled. The most common method is …
multiple levers by which they can be independently controlled. The most common method is …
Burden-driven feedback control of gene expression
Cells use feedback regulation to ensure robust growth despite fluctuating demands for
resources and differing environmental conditions. However, the expression of foreign …
resources and differing environmental conditions. However, the expression of foreign …
A heterogeneous microbial consortium producing short-chain fatty acids from lignocellulose
INTRODUCTION Consortia of microorganisms are a promising alternative to monocultures
for complex biotransformations because of their inherent advantages, such as the …
for complex biotransformations because of their inherent advantages, such as the …
Pyruvate-responsive genetic circuits for dynamic control of central metabolism
Dynamic regulation is a promising strategy for fine-tuning metabolic fluxes in microbial cell
factories. However, few of these synthetic regulatory systems have been developed for …
factories. However, few of these synthetic regulatory systems have been developed for …
[HTML][HTML] Dynamic control in metabolic engineering: Theories, tools, and applications
Metabolic engineering has allowed the production of a diverse number of valuable
chemicals using microbial organisms. Many biological challenges for improving bio …
chemicals using microbial organisms. Many biological challenges for improving bio …
Transcription-factor-based biosensor engineering for applications in synthetic biology
Transcription-factor-based biosensors (TFBs) are often used for metabolite detection,
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
adaptive evolution, and metabolic flux control. However, designing TFBs with superior …
Design of a programmable biosensor-CRISPRi genetic circuits for dynamic and autonomous dual-control of metabolic flux in Bacillus subtilis
Dynamic regulation is an effective strategy for fine-tuning metabolic pathways in order to
maximize target product synthesis. However, achieving dynamic and autonomous up-and …
maximize target product synthesis. However, achieving dynamic and autonomous up-and …
Quorum sensing for population-level control of bacteria and potential therapeutic applications
S Wu, J Liu, C Liu, A Yang, J Qiao - Cellular and Molecular Life Sciences, 2020 - Springer
Quorum sensing (QS), a microbial cell-to-cell communication process, dynamically regulates
a variety of metabolism and physiological activities. In this review, we provide an update on …
a variety of metabolism and physiological activities. In this review, we provide an update on …