Mitochondrial dysfunction: roles in skeletal muscle atrophy
X Chen, Y Ji, R Liu, X Zhu, K Wang, X Yang… - Journal of Translational …, 2023 - Springer
Mitochondria play important roles in maintaining cellular homeostasis and skeletal muscle
health, and damage to mitochondria can lead to a series of pathophysiological changes …
health, and damage to mitochondria can lead to a series of pathophysiological changes …
Inflammation: roles in skeletal muscle atrophy
Y Ji, M Li, M Chang, R Liu, J Qiu, K Wang, C Deng… - Antioxidants, 2022 - mdpi.com
Various diseases can cause skeletal muscle atrophy, usually accompanied by inflammation,
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …
mitochondrial dysfunction, apoptosis, decreased protein synthesis, and enhanced …
Potential therapeutic strategies for skeletal muscle atrophy
L Huang, M Li, C Deng, J Qiu, K Wang, M Chang… - Antioxidants, 2022 - mdpi.com
The maintenance of muscle homeostasis is vital for life and health. Skeletal muscle atrophy
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
not only seriously reduces people's quality of life and increases morbidity and mortality, but …
[HTML][HTML] Chronic kidney disease-induced muscle atrophy: molecular mechanisms and promising therapies
K Wang, Q Liu, M Tang, G Qi, C Qiu, Y Huang… - Biochemical …, 2023 - Elsevier
Chronic kidney disease (CKD) is a high-risk chronic catabolic disease due to its high
morbidity and mortality. CKD is accompanied by many complications, leading to a poor …
morbidity and mortality. CKD is accompanied by many complications, leading to a poor …
Prevalence and mechanisms of skeletal muscle atrophy in metabolic conditions
Skeletal muscle atrophy is prevalent in a myriad of pathological conditions, such as
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …
diabetes, denervation, long-term immobility, malnutrition, sarcopenia, obesity, Alzheimer's …
The vicious cycle of type 2 diabetes mellitus and skeletal muscle atrophy: clinical, biochemical, and nutritional bases
JM Lopez-Pedrosa, M Camprubi-Robles… - Nutrients, 2024 - mdpi.com
Today, type 2 diabetes mellitus (T2DM) and skeletal muscle atrophy (SMA) have become
increasingly common occurrences. Whether the onset of T2DM increases the risk of SMA or …
increasingly common occurrences. Whether the onset of T2DM increases the risk of SMA or …
Sarcopenia in a type 2 diabetic state: reviewing literature on the pathological consequences of oxidative stress and inflammation beyond the neutralizing effect of …
N Muvhulawa, SE Mazibuko-Mbeje, D Ndwandwe… - Life Sciences, 2023 - Elsevier
Sarcopenia remains one of the major pathological features of type 2 diabetes (T2D),
especially in older individuals. This condition describes gradual loss of muscle mass …
especially in older individuals. This condition describes gradual loss of muscle mass …
Ectodysplasin A2 receptor signaling in skeletal muscle pathophysiology
SD Özen, S Kir - Trends in Molecular Medicine, 2024 - cell.com
Skeletal muscle is essential in generating mechanical force and regulating energy
metabolism and body temperature. Pathologies associated with muscle tissue often lead to …
metabolism and body temperature. Pathologies associated with muscle tissue often lead to …
Altered m6A RNA methylation governs denervation-induced muscle atrophy by regulating ubiquitin proteasome pathway
J Sun, H Zhou, Z Chen, H Zhang, Y Cao, X Yao… - Journal of Translational …, 2023 - Springer
Background Denervation-induced muscle atrophy is complex disease involving multiple
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
biological processes with unknown mechanisms. N6-methyladenosine (m6A) participates in …
Protective Properties of Spheroidal Taxifolin Form in Streptozotocin-Induced Diabetic Rats
A Taldaev, AD Savina, VV Olicheva, SV Ivanov… - International Journal of …, 2023 - mdpi.com
One of the key factors in the pathogenesis of diabetes and its complications is oxidative
stress. To inhibit this process, antioxidants may be helpful. Herein, we focused on the …
stress. To inhibit this process, antioxidants may be helpful. Herein, we focused on the …