Immune landscape and redox imbalance during neurological disorders in COVID-19

A Thakur, V Sharma, S Averbek, L Liang… - Cell death & …, 2023 - nature.com
Abstract The outbreak of Coronavirus Disease 2019 (COVID-19) has prompted the scientific
community to explore potential treatments or vaccines against severe acute respiratory …

A comparison of etiology, pathogenesis, vaccinal and antiviral drug development between influenza and COVID-19

J Luo, Z Zhang, S Zhao, R Gao - International journal of molecular …, 2023 - mdpi.com
Influenza virus and coronavirus, two kinds of pathogens that exist widely in nature, are
common emerging pathogens that cause respiratory tract infections in humans. In December …

[HTML][HTML] Clinical characteristics of a COVID-19 cohort treated at UCLA Ronald Reagan Medical Center during the breaking phase of the pandemic: A retrospective …

B Zhou, NC Zong, Y Zhang, Y Huang, JY Youn, H Cai - Redox Biology, 2024 - Elsevier
To this date, COVID-19 remains an unresolved pandemic, and the impairment of redox
homeostasis dictates the severity of clinical outcomes. Here we examined initial UCLA …

Nitrite Attenuates the In Vitro Inflammatory Response of Immune Cells to the SARS-CoV-2 S Protein without Interfering in the Antioxidant Enzyme Activation

MD Ferrer, C Reynés, L Jiménez, G Malagraba… - International journal of …, 2024 - mdpi.com
SARS-CoV-2 induces a hyperinflammatory reaction due to the excessive release of
cytokines during the immune response. The bacterial endotoxin lipopolysaccharide (LPS) …

Superoxide dismutase alterations in COVID-19: implications for disease severity and mortality prediction in the context of omicron variant infection

J Chu, L Hua, X Liu, H Xiong, F Jiang, W Zhou… - Frontiers in …, 2024 - frontiersin.org
Background In the few reports to date, the changes in superoxide dismutase (SOD), a key
factor in cellular protection against superoxide, in COVID-19 have been very inconsistent …

A pilot study of mitochondrial response to an in vivo prosthetic joint Staphylococcus aureus infection model

N Bouji, E Meadows, JM Hollander… - Journal of …, 2024 - Wiley Online Library
Prosthetic joint infections (PJI) are associated with orthopaedic morbidity and mortality.
Mitochondria, the “cell's powerhouses,” are thought to play crucial roles in infection …

An electron paramagnetic resonance time‐course study of oxidative stress in the plasma of electronic cigarette exposed rats

M Velayutham, A Mills, VV Khramtsov… - Experimental …, 2024 - Wiley Online Library
The long‐term consequences of electronic cigarette (Ecig) use in humans are not yet known,
but it is known that Ecig aerosols contain many toxic compounds of concern. We have …

Bioinformatics and systems-biology approach to identify common pathogenic mechanisms for COVID-19 and systemic lupus erythematosus

Y Wu, Y Li, Y Zhou, X Bai, Y Liu - Autoimmunity, 2024 - Taylor & Francis
Abstract Background The Coronavirus disease 2019 (COVID-19) pandemic has brought a
heavy burden to the world, interestingly, it shares many clinical symptoms with systemic …

Influenza virus replication is affected by glutaredoxin1-mediated protein deglutathionylation

P Checconi, C Coni, D Limongi, S Baldelli… - The FASEB …, 2023 - iris.uniroma1.it
Several redox modifications have been described during viral infection, including influenza
virus infection, but little is known about glutathionylation and this respiratory virus …

Urate Biology and Biochemistry: A Year in Review 2022

RD King, EE Kelley - Gout, Urate, and Crystal Deposition Disease, 2023 - mdpi.com
The past year generated significant change and advancement of the urate field with novel
insights regarding the role of uric acid (UA) in multiple pathophysiologic processes from gout …