Heteroatoms as well as heterocyclic scaffolds are frequently present as the common cores in
a plethora of active pharmaceuticals natural products. Statistically, more than 85% of all …

This review which is the second in this series summarises the most common synthetic routes
as applied to the preparation of many modern pharmaceutical compounds categorised as …

Heterocycles are among the well-established classes of compounds, constituting a wide
range of organic molecules. These structural motifs not only have a dominant presence in a …

Described herein is the enantioselective synthesis of Hantzsch‐type 1, 4‐dihydropyridines
(DHPs), which are frequently contained in pharmaceuticals. Readily available symmetrical …

One of the most important steps in the synthesis of 1, 4-dihydropyridine (1, 4-DHP)
amphiphiles is the bromination of methyl groups in positions 2 and 6 of the entire ring …

We synthesized 1, 4-dihydropyridine skeleton using aza-Diels–Alder reaction under the
microwave irradiation condition which has become a powerful method for the rapid …

The mild bromine-magnesium exchange reaction using i-PrMgBr in THF on the 2-
bromomethyl-1, 4-dihydropyridine Hantzsch esters allowed the synthesis of highly …

The synthesis and pharmacological evaluation of a series of 2-[(arylsulfonyl) methyl]-4-aryl-5-
cyano-l, 4-dihydro-pyridine-3-carboxylic acid esters and analogues are described. These …

Abstract Asymmetrical 1, 4‐dihydropyridine esters 3a and 3i–k were synthesized from the
symmetrical precursor 1 through the intermediate 2‐bromomethyl derivative 2. Then …

FORMATION, SYNTHETIC UTILITY AND STRUCTURE ELUCIDATION OF A 2-BROMOMETHYL
1,4-DIHYDROPYRIDINE Page 1 Tehhedrm Latea. Vo1.31. No.10. pp 1479-1482 1990 …