Periodontitis is an inflammatory disease of oxidative stress: We should treat it that way

FSC Sczepanik, ML Grossi, M Casati… - Periodontology …, 2020 - Wiley Online Library
Periodontitis is a highly prevalent disease. As it progresses, it causes serious morbidity in
the form of periodontal abscesses and tooth loss and, in the latter stages, pain. It is also now …

Th17 cells and the IL-23/IL-17 axis in the pathogenesis of periodontitis and immune-mediated inflammatory diseases

K Bunte, T Beikler - International journal of molecular sciences, 2019 - mdpi.com
Innate immunity represents the semi-specific first line of defense and provides the initial host
response to tissue injury, trauma, and pathogens. Innate immunity activates the adaptive …

The case for periodontitis in the pathogenesis of rheumatoid arthritis

J Potempa, P Mydel, J Koziel - Nature Reviews Rheumatology, 2017 - nature.com
Rheumatoid arthritis (RA), an autoimmune disease that affects∼ 1% of the human
population, is driven by autoantibodies that target modified self-epitopes, whereas∼ 11% of …

Periodontitis and rheumatoid arthritis: What have we learned about their connection and their treatment?

J González‐Febles, M Sanz - Periodontology 2000, 2021 - Wiley Online Library
Rheumatoid arthritis and periodontitis are chronic inflammatory diseases defined
respectively by the destruction of the articular cartilage and tooth‐supporting periodontal …

[HTML][HTML] Periodontitis and periodontopathic bacteria as risk factors for rheumatoid arthritis: A review of the last 10 years

T Kobayashi, PM Bartold - Japanese Dental Science Review, 2023 - Elsevier
Rheumatoid arthritis (RA) is characterized by chronic inflammatory destruction of joint tissue
and is caused by an abnormal autoimmune response triggered by interactions between …

Rheumatoid Arthritis-Associated Mechanisms of Porphyromonas gingivalis and Aggregatibacter actinomycetemcomitans

E Gómez-Bañuelos, A Mukherjee, E Darrah… - Journal of clinical …, 2019 - mdpi.com
Rheumatoid arthritis (RA) is an autoimmune disease of unknown etiology characterized by
immune-mediated damage of synovial joints and antibodies to citrullinated antigens …

Periodontitis and rheumatoid arthritis: an update 2012‐2017

PM Bartold, I Lopez‐Oliva - Periodontology 2000, 2020 - Wiley Online Library
Rheumatoid arthritis and chronic periodontitis are both chronic inflammatory diseases
characterized by an exacerbated inflammatory reaction that leads to destruction of bone and …

Periodontitis and rheumatoid arthritis—Global efforts to untangle two complex diseases

I Lopez‐Oliva, J Malcolm, S Culshaw - Periodontology 2000, 2024 - Wiley Online Library
Understanding the impact of oral health on rheumatoid arthritis (RA) will inform how best to
manage patients with both periodontitis and RA. This review seeks to provide an update on …

Implications of Porphyromonas gingivalis peptidyl arginine deiminase and gingipain R in human health and diseases

YC Chow, HC Yam, B Gunasekaran, WY Lai… - Frontiers in Cellular …, 2022 - frontiersin.org
Porphyromonas gingivalis is a major pathogenic bacterium involved in the pathogenesis of
periodontitis. Citrullination has been reported as the underlying mechanism of the …

New insights into inflammatory osteoclast precursors as therapeutic targets for rheumatoid arthritis and periodontitis

E Hascoët, F Blanchard, C Blin-Wakkach, J Guicheux… - Bone Research, 2023 - nature.com
Rheumatoid arthritis (RA) and periodontitis are chronic inflammatory diseases leading to
increased bone resorption. Preventing this inflammatory bone resorption is a major health …