[PDF][PDF] Endometrial carcinomas: correlation between ER, PR, Ki67 status and histopathological prognostic parameters

SC Stoian, C Simionescu, CL Mărgăritescu… - Rom J Morphol …, 2011 - rjme.ro
We present a retrospective histopathological study that included a total of 22 endometrial
carcinomas, from patients that were operated in the Obstetrics and Gynecology Clinics of the …

Estrogen receptor status, determined by immunohistochemistry, as a predictor of the recurrence of stage I endometrial carcinoma

PA Gehrig, L Van Le, B Olatidoye, J Geradts - Cancer, 1999 - Wiley Online Library
BACKGROUND The aim of this study was to compare the concordance between
immunohistochemical (IHC) and biochemical (RIA) methods for determining hormone …

Epigenetic-mediated upregulation of progesterone receptor B gene in endometrial cancer cell lines

Y Xiong, SC Dowdy, JG Bosquet, Y Zhao… - Gynecologic …, 2005 - Elsevier
OBJECTIVES.: To determine if epigenetic interference can restore progesterone receptor-B
(PR-B) expression in PR-B negative endometrial adenocarcinoma cell lines, and to …

DACH1 suppresses epithelial to mesenchymal transition (EMT) through Notch1 pathway and reverses progestin resistance in endometrial carcinoma

Q Zhou, W Li, D Kong, Z Liu, Z Shi, X Ma, Y Li… - Cancer …, 2019 - Wiley Online Library
Progestin resistance limits the effectiveness of progestin therapy in endometrial carcinoma
for patients who desire to preserve fertility. To investigate the molecular mechanism of …

[HTML][HTML] Endometrial cancer: reviving progesterone therapy in the molecular age

S Yang, KW Thiel, K De Geest… - Discovery …, 2011 - discoverymedicine.com
Endometrial cancer is the most common gynecologic malignancy and represents a major
health concern because overall five-year survival rates have not improved in the last three …

Tamoxifen in combination with cytotoxic chemotherapy in advanced epithelial ovarian cancer. A prospective randomized trial

PE Schwartz, JT Chambers, EI Kohorn, SK Chambers… - Cancer, 1989 - Wiley Online Library
One hundred patients with Stage III and IV epithelial ovarian cancer participated in a
prospective randomized study to determine whether the addition of tamoxifen, an estrogen …

Immunohistochemical labelling of steroid receptors in normal and malignant human endometrium

I Mylonas, J Makovitzky, K Friese, U Jeschke - Acta histochemica, 2009 - Elsevier
For several years it was generally believed that only a single estrogen receptor (ER) and
progesterone receptor (PR) existed. However, the discovery of a new ER (ERβ) with …

Protein kinase C alpha expression is inversely related to ER status in endometrial carcinoma: possible role in AP-1-mediated proliferation of ER-negative endometrial …

DB Fournier, M Chisamore, JR Lurain… - Gynecologic …, 2001 - Elsevier
Objective. Tamoxifen is the most widely used antiestrogen to treat all stages of estrogen-
receptor (ER)-positive breast cancers. However, tamoxifen acts as a partial estrogen in the …

Steroid receptor concentrations in endometrial carcinoma: effect on survival in surgically staged patients

N Kadar, JH Malfetano, HD Homesley - Gynecologic oncology, 1993 - Elsevier
Estrogen and progesterone receptor concentrations were measured in the primary tumors of
137 surgically staged women with clinical stages I and II endometrial carcinoma. For each …

Prognostic significance and clinical importance of estrogen receptor α and β in human endometrioid adenocarcinomas

I Mylonas - Oncology reports, 2010 - spandidos-publications.com
Human endometrial cancer expresses both the known estrogen receptors (ER-α and ER-β).
The significance of the relative expression of both ER subtypes in endometrial …