Studies with temporal or spatial resolution are crucial to understand the molecular dynamics
and spatial dependencies underlying a biological process or system. With advances in high …

The development of spatial transcriptomics (ST) technologies has transformed genetic
research from a single-cell data level to a two-dimensional spatial coordinate system and …

The mammalian brain consists of millions to billions of cells that are organized into many cell
types with specific spatial distribution patterns and structural and functional properties …

In mammalian brains, millions to billions of cells form complex interaction networks to enable
a wide range of functions. The enormous diversity and intricate organization of cells have …

Here we report the generation of a multimodal cell census and atlas of the mammalian
primary motor cortex as the initial product of the BRAIN Initiative Cell Census Network …

A mammalian brain is composed of numerous cell types organized in an intricate manner to
form functional neural circuits. Single-cell RNA sequencing allows systematic identification …

Dendritic and axonal morphology reflects the input and output of neurons and is a defining
feature of neuronal types,, yet our knowledge of its diversity remains limited. Here, to …

The anatomy of the mammalian visual system, from the retina to the neocortex, is organized
hierarchically. However, direct observation of cellular-level functional interactions across this …

Prefrontal cortex (PFC) is the cognitive center that integrates and regulates global brain
activity. However, the whole-brain organization of PFC axon projections remains poorly …

Neurons are frequently classified into distinct types on the basis of structural, physiological,
or genetic attributes. To better constrain the definition of neuronal cell types, we …