Along with the tri-lineage of bone, cartilage and fat, human mesenchymal stem cells
(hMSCs) retain neural lineage potential. Multiple factors have been described that influence …

Human mesenchymal stem cells (hMSCs) have three key properties that make them
desirable for stem cell therapeutics: differentiation capacity, trophic activity, and ability to self …

The possible use of cell therapies for neurological lesions and disorders is regarded as a
very promising strategy. However, many issues related to cell type, tissue donor, expected …

Background & Aims Despite significant advances in the treatment of Crohn's disease (CD),
most patients still develop stricturing or penetrating complications that require surgical …

The possibility of treating degenerative diseases by stem cell-based approaches is a
promising therapeutical option. Among major concerns for the clinical application of stem …

The rates of incidence and prevalence of Crohn's disease and ulcerative colitis, the two
major forms of inflammatory bowel disease (IBD), are rising. Estimates indicate> 1 million …

A plethora of both acute and chronic conditions, including traumatic, degenerative,
malignant, or congenital disorders, commonly induce bone disorders often associated with …

Performing '-omics' analyses on heterogeneous biological tissue samples, such as blood or
bone marrow, can lead to biased or even erroneous results, particularly when the targeted …

Mesenchymal stem cells (MSC) are a unique population of adult stem cells that have the
capacity to differentiate into numerous cell types as well as the ability to modulate the …

Transplantation is the treatment of choice for many diseases that result in organ failure, but
its success is limited by organ rejection. Stem cell therapy has emerged in the last years as a …