Curcumin is a constituent (up to∼ 5%) of the traditional medicine known as turmeric. Interest
in the therapeutic use of turmeric and the relative ease of isolation of curcuminoids has led …

Dietary polyphenols have been the focus of major interest for their potential benefits on
human health. Several preclinical studies have been conducted to provide a rationale for …

Alzheimer's disease (AD) is the number one neurovegetative disease, but its treatment
options are relatively few and ineffective. In efforts to discover new strategies for AD therapy …

Alzheimer's disease (AD) is a neurodegenerative disorder of the elderly. As the prevalence
of AD rises in the 21st century, there is an urgent need for the development of effective …

Curcumin, the dietary polyphenol isolated from Curcuma longa (turmeric), is commonly used
as an herb and spice worldwide. Because of its bio-pharmacological effects curcumin is also …

The production of soluble amyloid-β oligomers (AβOs) and the activation of inflammation are
two important early steps in the pathogenesis of Alzheimer's disease (AD). The central role …

Many chronic human diseases, including multiple neurodegenerative diseases, are
associated with deleterious protein aggregates, also called protein amyloids. One common …

In aging and neurodegenerative diseases, loss of distinct type of neurons characterizes
disease-specific pathological and clinical features, and mitochondria play a pivotal role in …

Curcumin is a polyphenolic natural compound with diverse and attractive biological
properties, which may prevent or ameliorate pathological processes underlying age-related …

Curcumin is a multitherapeutic agent with great therapeutic potential in central nervous
system (CNS) diseases. In the current study, curcumin was encapsulated in solid lipid …