[HTML][HTML] Review of hybrid PLGA nanoparticles: Future of smart drug delivery and theranostics medicine

J Ghitman, EI Biru, R Stan, H Iovu - Materials & Design, 2020 - Elsevier
The concept of PLGA-lipid hybrid nanoparticles arose as a motivation for developing drug
delivery systems with versatile physical and chemical properties, unequivocal therapeutic …

[HTML][HTML] Bile acids activated receptors regulate innate immunity

S Fiorucci, M Biagioli, A Zampella - Frontiers in immunology, 2018 - frontiersin.org
Once known exclusively for their role in nutrients absorption, primary bile acids,
chenodeoxycholic and cholic acid, and secondary bile acids, deoxycholic and lithocholic …

A STAT3 palmitoylation cycle promotes TH17 differentiation and colitis

M Zhang, L Zhou, Y Xu, M Yang, Y Xu, GP Komaniecki… - Nature, 2020 - nature.com
Cysteine palmitoylation (S-palmitoylation) is a reversible post-translational modification that
is installed by the DHHC family of palmitoyltransferases and is reversed by several acyl …

[HTML][HTML] Biologics for inflammatory bowel disease and their safety in pregnancy: a systematic review and meta-analysis

OH Nielsen, JM Gubatan, CB Juhl, SE Streett… - Clinical …, 2022 - Elsevier
Background & Aims Biologics are used routinely in pregnant women with inflammatory
bowel disease (IBD), but large-scale data reporting adverse pregnancy outcomes among …

Emerging pharmacotherapy for inflammatory bowel diseases

H Luo, G Cao, C Luo, D Tan, CT Vong, Y Xu… - Pharmacological …, 2022 - Elsevier
Inflammatory bowel disease (IBD) refers to a gamut of disorders that are characterized by
chronic intestinal inflammation, including ulcerative colitis (UC) and Crohn's disease (CD) …

Role of interleukin-6-mediated inflammation in the pathogenesis of inflammatory bowel disease: Focus on the available therapeutic approaches and gut microbiome

A Shahini, A Shahini - Journal of Cell Communication and Signaling, 2023 - Springer
Inflammatory bowel disease (IBD) is considered a chronic inflammatory and multifactorial
disease of the gastrointestinal tract. Crohn's disease (CD) and ulcerative colitis (UC) are two …

Inflammatory bowel disease: between genetics and microbiota

N Younis, R Zarif, R Mahfouz - Molecular biology reports, 2020 - Springer
Inflammatory bowel disease (IBD) is a chronic relapsing inflammatory disease that can
involve any part of the gastrointestinal tract. It includes two main disorders: Crohn's disease …

[HTML][HTML] Selective JAK1 inhibitors for the treatment of inflammatory bowel disease

OH Nielsen, TL Boye, J Gubatan, D Chakravarti… - Pharmacology & …, 2023 - Elsevier
Janus kinase (JAK) inhibitors, also known as jakinibs, are third-generation oral small
molecules that have expanded the therapeutic options for the management of chronic …

[HTML][HTML] Emerging therapies for inflammatory bowel disease

R Weisshof, K El Jurdi, N Zmeter, DT Rubin - Advances in therapy, 2018 - Springer
Inflammatory bowel disease (IBD) is a chronic heterogeneous group of diseases that has
undergone major advances in the understanding of its etiology and pathogenesis in recent …

[HTML][HTML] Inflammatory bowel disease: a stressed “gut/feeling”

Y Oligschlaeger, T Yadati, T Houben… - Cells, 2019 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and relapsing intestinal inflammatory
condition, hallmarked by a disturbance in the bidirectional interaction between gut and …