[HTML][HTML] Gender susceptibility to COVID-19: a review of the putative role of sex hormones and X chromosome
C Foresta, MS Rocca, A Di Nisio - Journal of endocrinological investigation, 2021 - Springer
Background The recent emergence of COVID-19 poses a global health emergency. One of
the most frequently reported data is sex-related severity and mortality: according to the last …
the most frequently reported data is sex-related severity and mortality: according to the last …
Environment and brain plasticity: towards an endogenous pharmacotherapy
Brain plasticity refers to the remarkable property of cerebral neurons to change their
structure and function in response to experience, a fundamental theoretical theme in the …
structure and function in response to experience, a fundamental theoretical theme in the …
[HTML][HTML] DNA methylation signatures triggered by prenatal maternal stress exposure to a natural disaster: Project Ice Storm
L Cao-Lei, R Massart, MJ Suderman, Z Machnes… - PloS one, 2014 - journals.plos.org
Background Prenatal maternal stress (PNMS) predicts a wide variety of behavioral and
physical outcomes in the offspring. Although epigenetic processes may be responsible for …
physical outcomes in the offspring. Although epigenetic processes may be responsible for …
Prenatal stress and epigenetics
In utero exposure to environmental stress in both animals and humans could result in long-
term epigenome alterations which further lead to consequences for adaptation and …
term epigenome alterations which further lead to consequences for adaptation and …
Guide and position of the international society of nutrigenetics/nutrigenomics on personalised nutrition: part 1-fields of precision nutrition
LR Ferguson, R De Caterina, U Görman, H Allayee… - Lifestyle …, 2016 - karger.com
Diversity in the genetic profile between individuals and specific ethnic groups affects nutrient
requirements, metabolism and response to nutritional and dietary interventions. Indeed …
requirements, metabolism and response to nutritional and dietary interventions. Indeed …
The effects of early life stress on the epigenome: from the womb to adulthood and even before
N Provençal, EB Binder - Experimental neurology, 2015 - Elsevier
Exposure to early life stress (ELS), such as childhood abuse and neglect is a well
established major risk factor for developing psychiatric and behavioral disorders later in life …
established major risk factor for developing psychiatric and behavioral disorders later in life …
[HTML][HTML] Unraveling the functional role of DNA demethylation at specific promoters by targeted steric blockage of DNA methyltransferase with CRISPR/dCas9
DM Sapozhnikov, M Szyf - Nature Communications, 2021 - nature.com
Despite four decades of research to support the association between DNA methylation and
gene expression, the causality of this relationship remains unresolved. Here, we reaffirm that …
gene expression, the causality of this relationship remains unresolved. Here, we reaffirm that …
Environmental programming of stress responses through DNA methylation: life at the interface between a dynamic environment and a fixed genome
Early experience permanently alters behavior and physiology. These effects are, in part,
mediated by sustained alterations in gene expression in selected brain regions. The critical …
mediated by sustained alterations in gene expression in selected brain regions. The critical …
The CpG dinucleotide and human genetic disease
DN Cooper, H Youssoufian - Human genetics, 1988 - Springer
Reports of single base-pair mutations within gene coding regions causing human genetic
disease were collated. Thirty-five per cent of mutations were found to have occurred within …
disease were collated. Thirty-five per cent of mutations were found to have occurred within …
Nongenetic inheritance and transgenerational epigenetics
M Szyf - Trends in molecular medicine, 2015 - cell.com
The idea that inherited genotypes define phenotypes has been paramount in modern
biology. The question remains, however, whether stable phenotypes could be also inherited …
biology. The question remains, however, whether stable phenotypes could be also inherited …