Cytogenetic and molecular aspects of gastric cancer: clinical implications

AD Panani - Cancer letters, 2008 - Elsevier
Gastric cancer is of major importance world-wide being the second most common cause of
cancer-related death in the world. According to Lauren's histological classification gastric …

[HTML][HTML] The role and clinical implications of the retinoblastoma (RB)-E2F pathway in gastric cancer

T Wu, L Wu - Frontiers in Oncology, 2021 - frontiersin.org
Gastric cancer is the most common malignant tumor in the digestive tract, with very high
morbidity and mortality in developing countries. The pathogenesis of gastric cancer is a …

[HTML][HTML] Prognostic significance of aberrant gene methylation in gastric cancer

J Shi, G Zhang, D Yao, W Liu, N Wang… - American journal of …, 2012 - ncbi.nlm.nih.gov
Promoter methylation acts as an important alternative to genetic alterations for gene
inactivation in gastric carcinogenesis. Although a number of gastric cancer-associated …

Early onset gastric cancer: on the road to unraveling gastric carcinogenesis

AN Milne, R Sitarz, R Carvalho… - Current molecular …, 2007 - ingentaconnect.com
Gastric cancer is thought to result from a combination of environmental factors and the
accumulation of specific genetic alterations due to increasing genetic instability, and …

MiR-215 modulates gastric cancer cell proliferation by targeting RB1

Y Deng, Z Huang, Y Xu, J Jin, W Zhuo, C Zhang… - Cancer letters, 2014 - Elsevier
Growing evidence indicates that miRNAs play critical roles in tumorigenesis and cancer
progression. Here, we report that miR-215 is significantly up-regulated in gastric cancer …

Current and future molecular diagnostics of gastric cancer

RSY Choi, WYX Lai, LTC Lee, WLC Wong… - Expert review of …, 2019 - Taylor & Francis
Introduction: Gastric cancer (GC) is the fifth most common cancer and confers the second-
highest mortality among other cancers. Improving the survival rates of GC patients requires …

Neoplasms arising in large gastric hyperplastic polyps: endoscopic and pathologic features

JY Ahn, KD Choi, J Roh, H Lim, KS Choi, JH Lee… - Gastrointestinal …, 2014 - Elsevier
Background Little is known about gastric neoplasms arising from hyperplastic polyps (HPs).
Objective To investigate the risk factors associated with neoplasms within HPs and to …

Expression of retinoblastoma and cyclin D1 in gastric carcinoma

D Arici, E Tuncer, H Ozer, G Simek… - Neoplasma, 2009 - avesis.cumhuriyet.edu.tr
Abnormal regulation of the cell cycle is a feature of many neoplasms. The role of cell cycle
regulators in oncogenesis has been investigated in many human tumors. Alteration of the …

Histologic and immunohistochemical differences between hereditary and sporadic diffuse gastric carcinoma

HE Lee, TC Smyrk, L Zhang - Human Pathology, 2018 - Elsevier
We aimed to identify histopathologic features unique in hereditary diffuse gastric cancer
(HDGC) by comparing with its sporadic counterpart (SDGC). 11 patients with confirmed …

Analysis of p16 gene mutation, deletion and methylation in patients with arseniasis produced by indoor unventilated-stove coal usage in Guizhou, China

AH Zhang, HH Bin, XL Pan, XG Xi - Journal of Toxicology and …, 2007 - Taylor & Francis
The aim of this study was to determine p16 gene mutation, deletion, and promoter 5′ CpG
island hypermethylation in peripheral blood mononuclear leukocyte of patients with …