[HTML][HTML] The antimicrobial peptides and their potential clinical applications

J Lei, L Sun, S Huang, C Zhu, P Li, J He… - American journal of …, 2019 - ncbi.nlm.nih.gov
Nowadays, the bacterial drug resistance leads to serious healthy problem worldwide due to
the long-term use and the abuse of traditional antibiotics result in drug resistance of bacteria …

The structure-mechanism relationship and mode of actions of antimicrobial peptides: A review

S Li, Y Wang, Z Xue, Y Jia, R Li, C He… - Trends in Food Science & …, 2021 - Elsevier
Background The rapid increase of drug resistance in conventional antibiotics promotes the
discovery and development of antimicrobial peptides (AMPs), which are important …

[HTML][HTML] Chemical modifications to increase the therapeutic potential of antimicrobial peptides

Y Han, M Zhang, R Lai, Z Zhang - Peptides, 2021 - Elsevier
The continued use of antibiotics has been accompanied by the rapid emergence and spread
of antibiotic-resistant strains of bacteria. Antimicrobial peptides (AMPs), also known as host …

Antimicrobial peptides: A potent alternative to antibiotics

M Rima, M Rima, Z Fajloun, JM Sabatier, B Bechinger… - Antibiotics, 2021 - mdpi.com
Antimicrobial peptides constitute one of the most promising alternatives to antibiotics since
they could be used to treat bacterial infections, especially those caused by multidrug …

Antimicrobial susceptibility testing of antimicrobial peptides to better predict efficacy

DK Mercer, MDT Torres, SS Duay, E Lovie… - Frontiers in cellular …, 2020 - frontiersin.org
During the development of antimicrobial peptides (AMP) as potential therapeutics,
antimicrobial susceptibility testing (AST) stands as an essential part of the process in …

Advances in molecular understanding of α-helical membrane-active peptides

I Kabelka, R Vacha - Accounts of Chemical Research, 2021 - ACS Publications
Conspectus Biological membranes separate the interior of cells or cellular compartments
from their outer environments. This barrier function of membranes can be disrupted by …

Revealing the mechanisms of synergistic action of two magainin antimicrobial peptides

B Bechinger, DW Juhl, E Glattard… - Frontiers in Medical …, 2020 - frontiersin.org
The study of peptide-lipid and peptide-peptide interactions as well as their topology and
dynamics using biophysical and structural approaches have changed our view how …

Antibacterial photodynamic therapy in the near-infrared region with a targeting antimicrobial peptide connected to a π-extended porphyrin

C Gourlot, A Gosset, E Glattard… - ACS Infectious …, 2022 - ACS Publications
The increase of antimicrobial resistance to conventional antibiotics is worldwide a major
health problem that requires the development of new bactericidal strategies. Antimicrobial …

Antimicrobial Peptide Cec4 Eradicates the Bacteria of Clinical Carbapenem-Resistant Acinetobacter baumannii Biofilm

W Liu, Z Wu, C Mao, G Guo, Z Zeng, Y Fei… - Frontiers in …, 2020 - frontiersin.org
The drug resistance rate of Acinetobacter baumannii increases year on year, and the drugs
available for the treatment of carbapenem-resistant A. baumannii (CRAB) infection are …

Rescuing humanity by antimicrobial peptides against colistin-resistant bacteria

MT Moghadam, A Mojtahedi, MM Moghaddam… - Applied microbiology …, 2022 - Springer
It has been about a century since the discovery of the first antibiotic, and during this period,
several antibiotics were produced and marketed. The production of high-potency antibiotics …