In human pathophysiology, the clash between microbial infection and host immunity
contributes to multiple diseases. Cystic fibrosis (CF) is a classical example of this …

Abdominal aortic aneurysms (AAAs) are local dilations of infrarenal segment of aortas.
Molecular mechanisms underlying the pathogenesis of AAA remain not fully clear. However …

The widespread use of biomaterials to support or replace body parts is increasingly
threatened by the risk of implant‐associated infections. In the quest for finding novel anti …

Despite considerable recent progress in defining neutrophil functions and behaviors in
tissue repair, much remains to be determined with regards to its overall role in the tissue …

The antimicrobial functions of neutrophils are facilitated by a defensive armamentarium of
proteins stored in granules, and by the formation of neutrophil extracellular traps (NETs) …

Inflammation occurs as a result of exposure of tissues and organs to harmful stimuli such as
microbial pathogens, irritants, or toxic cellular components. The primary physical …

Macrophages and neutrophils play a decisive role in host responses to intracellular bacteria
including the agent of tuberculosis (TB), M ycobacterium tuberculosis as they represent the …

Chemokines are recognized as the most critical mediators for selective neutrophil
recruitment during inflammatory conditions. Furthermore, they are considered fundamental …

Systemic autoimmune diseases are a group of disorders characterized by a failure in self-
tolerance to a wide variety of autoantigens. In genetically predisposed individuals, these …

Neutrophils and neutrophil-like cells are the major pathogen-fighting immune cells in
organisms ranging from slime molds to mammals. Central to their function is their ability to …