Spaceflight and its associated stressors, such as microgravity, radiation exposure,
confinement, circadian derailment and disruptive workloads represent an unprecedented …

Protein synthesis and degradation are dynamically regulated processes that act in concert to
control the accretion or loss of muscle mass. The present article focuses on the mechanisms …

Myostatin is a member of the transforming growth factor (TGF)-β superfamily. It is expressed
by animal and human skeletal muscle cells where it limits muscle growth and promotes …

The peroxisome proliferator-activated receptors, PPARα, PPARβ, and PPARγ, are a family of
transcription factors activated by a diversity of molecules including fatty acids and fatty acid …

There is a growing recognition that noncoding RNAs (ncRNA) play an important role in the
regulation of gene expression. A class of small (19–22 nt) ncRNAs, known as microRNAs …

The effect of microgravity on skeletal muscles has so far been examined in rat and mice only
after short-term (5–20 day) spaceflights. The mice drawer system (MDS) program …

Motivation To curate and organize expensive spaceflight experiments conducted aboard
space stations and maximize the scientific return of investment, while democratizing access …

MicroRNA in myogenesis and muscle atrophy : Current Opinion in Clinical Nutrition &
Metabolic Care MicroRNA in myogenesis and muscle atrophy : Current Opinion in Clinical …

MicroRNA (miRNA) represent a family of noncoding RNA of approximately 23 nucleotides
that regulate gene expression through a posttranscriptional mechanism. Originally …

A spaceflight has enormous influence on the health of space voyagers due to the combined
effects of microgravity and cosmic radiation. Known effects of microgravity (μ g) on cells are …