Involvement of cholinergic dysfunction and oxidative damage in the effects of simulated weightlessness on learning and memory in rats

Y Zhang, Q Wang, H Chen, X Liu, K Lv… - BioMed research …, 2018 - Wiley Online Library
The present study aimed to determine how the learning and memory gradually change with
the prolonged hindlimb unloading (HU) treatment in rats. Different HU durations (7 d, 14 d …

Role of microRNAs in the age-related changes in skeletal muscle and diet or exercise interventions to promote healthy aging in humans

RA McGregor, SD Poppitt, D Cameron-Smith - Ageing research reviews, 2014 - Elsevier
Progressive age-related changes in skeletal muscle mass and composition, underpin
decreases in muscle function, which can inturn lead to impaired mobility and quality of life in …

5‐Lipoxygenase‐dependent apoptosis of human lymphocytes in the International Space Station: data from the ROALD experiment

N Battista, MA Meloni, M Bari, N Mastrangelo… - The FASEB …, 2012 - Wiley Online Library
The functional adaptation of the immune system to the surrounding environment is also a
fundamental issue in space. It has been suggested that a decreased number of lymphocytes …

NASA GeneLab platform utilized for biological response to space radiation in animal models

JT McDonald, R Stainforth, J Miller, T Cahill… - Cancers, 2020 - mdpi.com
Background: Ionizing radiation from galactic cosmic rays (GCR) is one of the major risk
factors that will impact the health of astronauts on extended missions outside the protective …

Molt cycle regulation of protein synthesis in skeletal muscle of the blackback land crab, Gecarcinus lateralis, and the differential expression of a myostatin-like factor …

JA Covi, BD Bader, ES Chang… - Journal of Experimental …, 2010 - journals.biologists.com
In decapod crustaceans, claw muscle undergoes atrophy in response to elevated
ecdysteroids while thoracic muscle undergoes atrophy in response to unweighting. The …

MicroRNA in skeletal muscle development, growth, atrophy, and disease

A Kovanda, T Režen, B Rogelj - Wiley Interdisciplinary Reviews …, 2014 - Wiley Online Library
Micro RNAs (miRNAs) are short noncoding RNAs that are important global‐as well as tissue‐
and cell‐type‐specific regulators of gene expression. Muscle‐specific miRNAs or myomirs …

Noise-induced dysregulation of Quaking RNA binding proteins contributes to auditory nerve demyelination and hearing loss

CH Panganiban, JL Barth, L Darbelli… - Journal of …, 2018 - Soc Neuroscience
Noise exposure causes auditory nerve (AN) degeneration and hearing deficiency, though
the proximal biological consequences are not entirely understood. Most AN fibers and spiral …

Characterization of the skeletal muscle proteome in undernourished old rats

C Barbé, J Salles, C Chambon, C Giraudet… - International Journal of …, 2022 - mdpi.com
Aging is associated with a progressive loss of skeletal muscle mass and function termed
sarcopenia. Various metabolic alterations that occur with aging also increase the risk of …

[HTML][HTML] Simulated microgravity modulates differentiation processes of embryonic stem cells

V Shinde, S Brungs, M Henry, L Wegener… - Cellular Physiology and …, 2016 - karger.com
Background/Aims: Embryonic developmental studies under microgravity conditions in space
are very limited. To study the effects of altered gravity on the embryonic development …

Neural stem/progenitor cell properties of glial cells in the adult mouse auditory nerve

H Lang, Y Xing, LSN Brown, DJ Samuvel… - Scientific reports, 2015 - nature.com
The auditory nerve is the primary conveyor of hearing information from sensory hair cells to
the brain. It has been believed that loss of the auditory nerve is irreversible in the adult …