Acute daily psychological stress causes increased atrophic gene expression and myostatin-dependent muscle atrophy

DL Allen, GE McCall, AS Loh… - American Journal of …, 2010 - journals.physiology.org
Psychological stress is known to attenuate body size and lean body mass. We tested the
effects of 1, 3, or 7 days of two different models of psychological stress, 1 h of daily restraint …

Effects of resistance exercise combined with essential amino acid supplementation and energy deficit on markers of skeletal muscle atrophy and regeneration during …

NE Brooks, SM Cadena, E Vannier, G Cloutier… - Muscle & …, 2010 - Wiley Online Library
Spaceflight and bed rest (BR) lead to muscle atrophy. This study assessed the effect of
essential amino acid (EAA) supplementation and resistance training with decreased energy …

Epigenetic regulation of muscle phenotype and adaptation: a potential role in COPD muscle dysfunction

E Barreiro, JI Sznajder - Journal of applied physiology, 2013 - journals.physiology.org
Quadriceps muscle dysfunction occurs in one-third of patients with chronic obstructive
pulmonary disease (COPD) in very early stages of their condition, even prior to the …

Expression changes in human skeletal muscle mi RNA s following 10 days of bed rest in young healthy males

T Režen, A Kovanda, O Eiken, IB Mekjavic… - Acta …, 2014 - Wiley Online Library
Aim Studies in humans show global changes in mRNA and protein expression occur in
human skeletal muscle during bed rest. As micro RNA s are important regulators of …

Role of E2-Ub-conjugating enzymes during skeletal muscle atrophy

C Polge, D Attaix, D Taillandier - Frontiers in physiology, 2015 - frontiersin.org
The Ubiquitin Proteasome System (UPS) is a major actor of muscle wasting during various
physio-pathological situations. In the past 15 years, increasing amounts of data have …

Fenofibrate, a PPARα agonist, decreases atrogenes and myostatin expression and improves arthritis-induced skeletal muscle atrophy

E Castillero, MP Nieto-Bona… - American Journal …, 2011 - journals.physiology.org
Arthritis is a chronic inflammatory illness that induces cachexia, which has a direct impact on
morbidity and mortality. Fenofibrate, a selective PPARα activator prescribed to treat human …

Effects of walking, running, and skipping under simulated reduced gravity using the NASA Active Response Gravity Offload System (ARGOS)

S Orr, J Casler, J Rhoades, P de León - Acta Astronautica, 2022 - Elsevier
Past research efforts have focused on the energy difference between altered locomotion
methods in reduced gravity at different speeds, suggesting that skipping is energetically …

miR-206 enforces a slow muscle phenotype

KK Bjorkman, MG Guess, BC Harrison… - Journal of cell …, 2020 - journals.biologists.com
Striated muscle is a highly specialized collection of tissues with contractile properties that
vary according to functional needs. Although muscle fiber types are established postnatally …

Simulated microgravity inhibits C2C12 myogenesis via phospholipase D2-induced Akt/FOXO1 regulation

MO Baek, CB Ahn, HJ Cho, JY Choi, KH Son… - Scientific reports, 2019 - nature.com
The skeletal muscle system has evolved to maintain body posture against a constant
gravitational load. Mammalian target of rapamycin (mTOR) regulates the mechanically …

Elastogenic inductability of smooth muscle cells from a rat model of late stage abdominal aortic aneurysms

CE Gacchina, P Deb, JL Barth… - Tissue Engineering Part …, 2011 - liebertpub.com
Although abdominal aortic aneurysms (AAA) can be potentially stabilized by inhibiting
inflammatory cell recruitment and their release of proteolytic enzymes, active AAA …