Continuous preparation of sustained release vildagliptin nanoparticles using tubular microreactor approach

A Patil, S Pardeshi, M Kapase, P Patil, M More… - Drying …, 2024 - Taylor & Francis
This investigation used a tubular microreactor to produce Vildagliptin (VLG) loaded ethyl
cellulose (EC) nanoparticles (NPs) for sustained delivery of a drug. A central composite …

Gelatin–κ-carrageenan polyelectrolyte complex hydrogel compositions for the design and development of extended-release pellets

RO Sonawane, SD Patil - International Journal of Polymeric …, 2017 - Taylor & Francis
Present investigation was aimed to develop Zaltoprofen-loaded extended-release (ER)
pellets formulation for prolonged release. The matrix type of pellets was prepared by …

Design, optimization and characterization of atorvastatin loaded chitosan-based polyelectrolyte complex nanoparticles based transdermal patch

P Patil, A Vankani, K Sawant - International Journal of Biological …, 2024 - Elsevier
Aim Atorvastatin (ATO) loaded chitosan-based polyelectrolyte complex nanoparticles
(PECN) incorporated transdermal patch was developed to enhance its skin permeability and …

Greener approach for synthesis of N, N, N-trimethyl chitosan (TMC) using ternary deep eutectic solvents (TDESs)

T Mahajan, P Bangde, P Dandekar, R Jain - Carbohydrate Research, 2020 - Elsevier
Abstract N, N, N-trimethyl chitosan (TMC), quaternized hydrophilic derivative of chitosan, has
been projected to have wide applications in the pharmaceutical industry owing to its …

Central composite rotatable design for optimization of budesonide-loaded cross-linked chitosan–dextran sulfate nanodispersion: characterization, in vitro diffusion …

DS Bodas, PP Ige - Drug Development and Industrial Pharmacy, 2019 - Taylor & Francis
Budesonide is a BCS class II drug with low water solubility (0.045 mg/mL) and low oral
bioavailability (6–8%) due to high first pass effect. The aim is to prepare cross-linked …

Chitosan Nanoparticles for Intranasal Drug Delivery

H Omidian, EJ Gill, S Dey Chowdhury, LX Cubeddu - Pharmaceutics, 2024 - mdpi.com
This manuscript explores the use of nanostructured chitosan for intranasal drug delivery,
targeting improved therapeutic outcomes in neurodegenerative diseases, psychiatric care …

[PDF][PDF] Mucoadhesive nanoparticles: A roadmap to encounter the challenge of rapid nasal mucociliary clearance

CV Pardeshi, AD Kulkarni, RO Sonawane… - Indian J. Pharm. Educ …, 2019 - ijper.org
The modulation of mucoadhesion at the nanoscale is a very challenging task before the
formulation scientists. Mucoadhesive nanoparticles are endowed with distinct properties …

[PDF][PDF] Formulation and evaluation of chitosan based polyelectrolyte complex of levodopa for nasal drug delivery

PS Avhad, RA Gupta, SN Firke, AB Roge… - International Journal of …, 2022 - academia.edu
Because chitosan is biodegradable, biocompatible, non-toxic, and mucoadhesive, it is
commonly used in the formulation of nasal drug delivery nanoparticles employing …

Pharmacokinetic/pulmokinetic analysis of optimized lung targeted spray dried ketotifen-dextran core shell nanocomplexes–in-microparticles

D El Baihary, R Osman, HM Abdel-Bar… - International journal of …, 2019 - Elsevier
A passive lung targeted system for controlled lung delivery of ketotifen (KT) was developed
based on the green complexation of dextran sulphate (DS) and KT. Achieving deep lung …

Self-Assembly of Soluble Chitosan Derivatives Nanoparticles for Vaccine: Synthesis, Characterization and Evaluation

J Liu, S Yu, W Qu, Z Jin, K Zhao - Polymers, 2021 - mdpi.com
Herein, a novel chitosan derivative nanoparticle was proposed to function as a delivery
carrier. First of all, an improvement was made to the way N-2-hydroxypropyl trimcthyl …