Drugs that affect cardiac metabolism: focus on perhexiline
CR Chong, B Sallustio, JD Horowitz - Cardiovascular drugs and therapy, 2016 - Springer
Approaches to the pharmacotherapy of angina pectoris have previously centred on the
concept that a transient imbalance between myocardial oxygen “demand” and supply within …
concept that a transient imbalance between myocardial oxygen “demand” and supply within …
Can perhexiline be utilized without long-term toxicity? A clinical practice audit
Background: Perhexiline, originally used as a first-line prophylactic antianginal agent, is now
regarded primarily as a treatment for otherwise refractory myocardial ischemia. Recent …
regarded primarily as a treatment for otherwise refractory myocardial ischemia. Recent …
Stereoselective handling of perhexiline: implications regarding accumulation within the human myocardium
Purpose Perhexiline is a prophylactic anti-ischaemic agent with weak calcium antagonist
effect which has been increasingly utilised in the management of refractory angina. The …
effect which has been increasingly utilised in the management of refractory angina. The …
Relationship between plasma, atrial and ventricular perhexiline concentrations in humans: insights into factors affecting myocardial uptake
Aim Little is known regarding the steady‐state uptake of drugs into the human myocardium.
Perhexiline is a prophylactic anti‐anginal drug which is increasingly also used in the …
Perhexiline is a prophylactic anti‐anginal drug which is increasingly also used in the …
A Pharmacological Approach towards Myocardial Protection: New Perspectives in Acute and Chronic Cardiac Disease
CR Chong - 2017 - digital.library.adelaide.edu.au
Several cardiac diseases include myocardial ischaemia (acute or chronic), heart failure
(systolic or diastolic) and left ventricular hypertrophy (either as a “primary” cause or …
(systolic or diastolic) and left ventricular hypertrophy (either as a “primary” cause or …