Adenosine triphosphate (ATP), an essential metabolic energy source, is released following
cell apoptosis or necrosis. It acts as a damage-associated molecule pattern to stimulate …

The artificial induction of tolerance in transplantation is gaining strength. In mice, a
differential role of extracellular adenosine (eADO) for regulatory and effector T cells (Tregs …

SUMMARY Glucagon-like peptide-1 receptor (GLP-1R) is a key regulator of glucose
metabolism known to be expressed by pancreatic b cells. We herein investigated the role of …

During the past years, solid allograft rejection has been considered the consequence of
either cellular-or antibody-mediated reaction both being part of the adaptive immune …

Lung transplantation has limited survival with current immunosuppression. ATP is released
from activated T cells, which act as costimulatory molecules through binding to the …

The P2X7 receptor is a trimeric ligand-gated cation channel present on immune and other
cells. Activation of this receptor by its natural ligand extracellular adenosine triphosphate …

Aims Insular cortex (IC) is involved in processing the information of pain. The aim of this
study was to investigate roles and mechanisms of P2X7 receptors (P2X7Rs) in IC in …

Significant strides have been made in our understanding of the immune system and its role
in cardiac transplant rejection. Despite the growing knowledge of immune responses, the …

Organ transplantation stands as a pivotal achievement in modern medicine, offering hope to
individuals with end-stage organ diseases. Advancements in immunology led to improved …

ATP and T-cell-mediated rejection : Current Opinion in Organ Transplantation ATP and T-cell-mediated
rejection : Current Opinion in Organ Transplantation Log in or Register Subscribe to journalSubscribe …