Background Our previous study demonstrated that regulatory B cells (Bregs) play an
indispensable role in dual anti-CD45RB/anti-TIM-1 antibody-induced transplantation …

Organ transplantation is the preferred paradigm for patients with end-stage organ failures.
Despite unprecedented successes, complications such as immune rejection, ischemia …

Foxp3 stability of vitamin C-treated induced-regulatory T cells (V-iTregs) is superior to that of
conventional iTregs (C-iTregs). However, the role of V-iTregs in allograft rejection under …

The role of the novel costimulatory molecule TIM4 in anti-islet response is unknown. We
explored TIM4 expression and targeting in Th1 (BALB/c islets into C57BL/6 mice) and Th2 …

Acute graft-versus-host disease (GvHD) is mediated by alloreactive donor-derived T cells
with a suitable T cell receptor recognizing recipient major histocompatibility complex or …

0 [1*] N1C= NC2= C1C ([5*]) C ([4*]) N (C ([8*])= O) C2 [3*].[3*] C1C2= C (CC ([4*]) N1C
([8*])= O) C ([7*])= NN2 [6*].[3*] C1C2= NN ([6*]) C ([7*])= C2CC ([4*]) N1C ([8*])= O …

Background. Antibody-mediated rejection (AMR) is a major cause of renal allograft
dysfunction and loss. Targeting B cells and/or donor-specific antibody removal using plasma …

Skeletal muscle (SM) is a heterogeneous and dynamic tissue that changes significantly in its
form and function in response to external and internal stimuli and throughout life, from …

Diabetes is a metabolic disorder characterized by elevation of glucose levels in the blood
that develops in humans as a result of genetic predisposition and environmental factors …

Heart transplantation was performed for the first time 40 years ago and it is now universally
considered the “gold standard” treatment for individuals suffering from end-stage heart …