Fast Self‐Assembly Dynamics of a β‐Sheet Peptide Soft Material

J Bertouille, S Kasas, C Martin, U Hennecke, S Ballet… - Small, 2023 - Wiley Online Library
Peptide‐based hydrogels are promising biocompatible materials for wound healing, drug
delivery, and tissue engineering applications. The physical properties of these …

High-resolution cryo-electron microscopy reveals the unique striated hollow structure of photocatalytic macrocyclic polydiacetylene nanotubes

NN Kadamannil, JM Heo, D Jang, R Zalk… - Journal of the …, 2022 - ACS Publications
High-resolution structures are crucial for understanding the functional properties of
nanomaterials. We applied single-particle cryo-electron microscopy (cryo-EM), a method …

Nucleation and growth of amyloid fibrils

S Jalali, R Zhang, MP Haataja… - The Journal of Physical …, 2023 - ACS Publications
The formation of amyloid fibrils is a complex phenomenon that remains poorly understood at
the atomic scale. Herein, we perform extended unbiased all-atom simulations in explicit …

Dynamic Control of Cyclic Peptide Assembly to Form Higher‐Order Assemblies

C Wu, H Zhang, N Kong, B Wu, X Lin… - Angewandte …, 2023 - Wiley Online Library
Chirality correction, asymmetry, ring‐chain tautomerism and hierarchical assemblies are
fundamental phenomena in nature. They are geometrically related and may impact the …

Phenol-soluble modulins PSMα3 and PSMβ2 form nanotubes that are cross-α amyloids

MAB Kreutzberger, S Wang… - Proceedings of the …, 2022 - National Acad Sciences
Phenol-soluble modulins (PSMs) are peptide-based virulence factors that play significant
roles in the pathogenesis of staphylococcal strains in community-associated and hospital …

Resolving the Nanoscale Structure of β-Sheet Peptide Self-Assemblies Using Single-Molecule Orientation–Localization Microscopy

W Zhou, CL O'Neill, T Ding, O Zhang, JS Rudra… - ACS …, 2024 - ACS Publications
Synthetic peptides that self-assemble into cross-β fibrils are versatile building blocks for
engineered biomaterials due to their modularity and biocompatibility, but their structural and …

Injectable tripeptide/polymer nanoparticles supramolecular hydrogel: a candidate for the treatment of inflammatory pathologies

M Criado-Gonzalez, E Espinosa-Cano… - … Applied Materials & …, 2022 - ACS Publications
Supramolecular peptide-based hydrogels attract great attention in several fields, ie,
biomedicine, catalysis, energy, and materials chemistry, due to the noncovalent nature of the …

Peptide-based nanomaterials: Building back better & beyond

VP Conticello - Current Opinion in Solid State and Materials Science, 2023 - Elsevier
The exquisite structure–function correlations observed for native protein filaments have
prompted research into the design of simpler peptide-based analogues that can be tailored …

Structures of synthetic helical filaments and tubes based on peptide and peptido-mimetic polymers

JG Miller, SA Hughes, C Modlin… - Quarterly Reviews of …, 2022 - cambridge.org
Synthetic peptide and peptido-mimetic filaments and tubes represent a diverse class of
nanomaterials with a broad range of potential applications, such as drug delivery, vaccine …

Atomic insights into amyloid-induced membrane damage

Y Yang, H Distaffen, S Jalali… - ACS Chemical …, 2022 - ACS Publications
Amphipathic peptides can cause biological membranes to leak either by dissolving their
lipid content via a detergent-like mechanism or by forming pores on the membrane surface …