Cardiovascular disease is the leading cause of death worldwide. Despite advancements in
diagnosis and treatment of cardiovascular disease, the incidence of cardiovascular disease …

Renal ischemia-reperfusion (IR) contributes to the development of ischemic acute renal
failure (ARF). Multi-factorial processes are involved in the development and progression of …

OBJECTIVE Despite the beneficial effects of resveratrol (RSV) on cardiovascular disease
and life span, its effects on type 2 diabetic nephropathy remain unknown. This study …

Autophagy, an evolutionary conserved intracellular lysosome-dependent catabolic process,
is an important mechanism for cellular homeostasis and survival during pathologic stress …

Recent studies have documented that remote organs are affected by ischemic injury to the
kidney. Here we studied whether the liver also suffers damage during induction of renal …

Background & Aims Hepatic ischemia-reperfusion injury (IRI), characterized by exogenous
antigen-independent local inflammation and hepatocellular death, represents a risk factor …

Acute kidney injury (AKI) is a major renal disease associated with high mortality rate and
increasing prevalence. Decades of research have suggested numerous chemical and …

Resveratrol is a nonflavonoid polyphenol with antioxidant, anticancer and antiinflammatory
properties. Moreover, it has been reported that this compound inhibits NF‐κB, which …

The possible protective effects of resveratrol (RVT) against cardiotoxicity were investigated
in Wistar albino rats treated with saline, saline+ doxorubicin (DOX; 20 mg/kg) or RVT (10 …

High-mobility group box 1 (HMGB1) undergoes acetylation, nuclear-to-cytoplasmic
translocation, and release from stressed kidneys, unleashing a signaling cascade of events …