Context: Papillary thyroid microcarcinoma (PTMC) usually has an excellent prognosis.
Objective: To evaluate the three-dimensional structures of PTMCs, using serial neck …

Background: Large-volume lymph node metastasis (LNM) is associated with poor clinical
outcomes in papillary thyroid microcarcinoma (PTMC) patients. However, sensitivity in the …

Second harmonic generation (SHG) microscopy is acknowledged as an established
imaging technique capable to provide information on the collagen architecture in tissues that …

Objectives Papillary thyroid microcarcinoma (PTMC) has an excellent prognosis with an
indolent disease course. However, some PTMC s have an aggressive course with lateral …

Aberrant expression of the guanine nucleotide exchange factor Tiam1 is implicated in the
invasive phenotype of many cancers. However, its involvement in thyroid carcinoma and …

The standard treatment regimen for locally recurrent lesions is total thyroidectomy, or
complete removal of the recurrent thyroid lesion within the thyroid bed. However …

Papillary thyroid cancer (PTC) is one of the most common endocrine malignancies
associated with significant morbidity and mortality. Although multiple studies have …

Thyroid disease is one of the most common endocrine problems around the world. Among
the numerous factors, exposure to environmental elements such as pesticides is associated …

Background SREBP1 is a well-known transcript factor regulating lipogenesis. It has been
reported to play an important role in tumor progress in recent years. However, the roles of …

Joseph F. Simeone, MD, is professor of radiology at Harvard Medical School. At
Massachusetts General Hospital, he has been director of the Division of Ultrasound. He has …