Plasticity and susceptibility of brain morphometry alterations to insufficient sleep

XJ Dai, J Jiang, Z Zhang, X Nie, BX Liu, L Pei… - Frontiers in …, 2018 - frontiersin.org
Background: Insufficient sleep is common in daily life and can lead to cognitive impairment.
Sleep disturbance also exists in neuropsychiatric diseases. However, whether and how …

Sleep, neuronal hyperexcitability, inflammation and neurodegeneration: Does early chronic short sleep trigger and is it the key to overcoming Alzheimer's disease?

A Ahnaou, W Drinkenburg - Neuroscience & Biobehavioral Reviews, 2021 - Elsevier
Evidence links neuroinflammation to Alzheimer's disease (AD); however, its exact
contribution to the onset and progression of the disease is poorly understood. Symptoms of …

The role of sleep in human declarative memory consolidation

SE Alger, AM Chambers, T Cunningham… - Sleep, neuronal plasticity …, 2015 - Springer
Through a variety of methods, researchers have begun unraveling the mystery of why
humans spend one-third of their lives asleep. Though sleep likely serves multiple functions …

Sleep-wake cycling and energy conservation: role of hypocretin and the lateral hypothalamus in dynamic state-dependent resource optimization

B Latifi, A Adamantidis, C Bassetti… - Frontiers in neurology, 2018 - frontiersin.org
The hypocretin (Hcrt) system has been implicated in a wide range of physiological functions
from sleep-wake regulation to cardiovascular, behavioral, metabolic, and thermoregulagtory …

State-dependent metabolic partitioning and energy conservation: A theoretical framework for understanding the function of sleep

MH Schmidt, TW Swang, IM Hamilton, JA Best - PloS one, 2017 - journals.plos.org
Metabolic rate reduction has been considered the mechanism by which sleep conserves
energy, similar to torpor or hibernation. This mechanism of energy savings is in conflict with …

Sleep and synaptic homeostasis

C Cirelli, G Tononi - Sleep, 2015 - academic.oup.com
We thank Dr. Heller for discussing in a recent editorial in SLEEP1 the implications of the
study by Dr. Aton and colleagues2 for the synaptic homeostasis hypothesis3 (SHY). Dr …

Computational analysis of gene regulation in animal sleep deprivation

H Wang, Y Liu, M Briesemann… - Physiological …, 2010 - journals.physiology.org
Sleep is an animal behavior shared by a wide range of species, suggesting that it must
serve fundamental functions. However, the functions and molecular mechanisms underlying …

Assessing REM sleep in mice using video data

BB McShane, RJ Galante, M Biber, ST Jensen… - Sleep, 2012 - academic.oup.com
Abstract Study Objectives: Assessment of sleep and its substages in mice currently requires
implantation of chronic electrodes for measurement of electroencephalogram (EEG) and …

Loss of sleep affects the ultrastructure of pyramidal neurons in the adolescent mouse frontal cortex

L De Vivo, AB Nelson, M Bellesi, J Noguti, G Tononi… - Sleep, 2016 - academic.oup.com
Abstract Study Objective The adolescent brain may be uniquely affected by acute sleep
deprivation (ASD) and chronic sleep restriction (CSR), but direct evidence is lacking. We …

Genetic dissection of sleep homeostasis

GM Mang, P Franken - Sleep, neuronal plasticity and brain function, 2015 - Springer
Sleep is a complex behavior both in its manifestation and regulation, that is common to
almost all animal species studied thus far. Sleep is not a unitary behavior and has many …