Host response mechanisms in periodontal diseases

N Silva, L Abusleme, D Bravo, N Dutzan… - Journal of Applied Oral …, 2015 - SciELO Brasil
Periodontal diseases usually refer to common inflammatory disorders known as gingivitis
and periodontitis, which are caused by a pathogenic microbiota in the subgingival biofilm …

Local drug delivery systems in the management of periodontitis: A scientific review

HR Rajeshwari, D Dhamecha, S Jagwani… - Journal of Controlled …, 2019 - Elsevier
Periodontitis (PD) is a microbial disease of tooth supporting tissues that results in
progressive destruction of surrounding soft and hard tissues with eventual tooth mobility and …

The impact of smoking on subgingival microflora: from periodontal health to disease

Y Jiang, X Zhou, L Cheng, M Li - Frontiers in microbiology, 2020 - frontiersin.org
Periodontal disease is one of the most common diseases of the oral cavity affecting up to
90% of the worldwide population. Smoking has been identified as a major risk factor in the …

Destructive and protective roles of cytokines in periodontitis: a re-appraisal from host defense and tissue destruction viewpoints

GP Garlet - Journal of dental research, 2010 - journals.sagepub.com
Periodontal diseases (PD) are chronic infectious inflammatory diseases characterized by the
destruction of tooth-supporting structures, being the presence of periodontopathogens …

Importance of virulence factors for the persistence of oral bacteria in the inflamed gingival crevice and in the pathogenesis of periodontal disease

G Dahlen, A Basic, J Bylund - Journal of clinical medicine, 2019 - mdpi.com
Periodontitis is a chronic inflammation that develops due to a destructive tissue response to
prolonged inflammation and a disturbed homeostasis (dysbiosis) in the interplay between …

Breaking bad: Manipulation of the host response by Porphyromonas gingivalis

G Hajishengallis, RJ Lamont - European journal of immunology, 2014 - Wiley Online Library
Recent metagenomic and mechanistic studies are consistent with a new model of
periodontal pathogenesis. This model proposes that periodontal disease is initiated by a …

An appraisal of the role of specific bacteria in the initial pathogenesis of periodontitis

PM Bartold, TE Van Dyke - Journal of clinical periodontology, 2019 - Wiley Online Library
Background Historically, inflammatory periodontal diseases (gingivitis and periodontitis)
have been recognized as being primarily of bacterial origin. Bacteria are necessary for …

Periodontal bacterial invasion and infection: contribution to atherosclerotic pathology

L Reyes, D Herrera, E Kozarov… - Journal of clinical …, 2013 - Wiley Online Library
Objective The objective of this review was to perform a systematic evaluation of the literature
reporting current scientific evidence for periodontal bacteria as contributors to …

The oral microbiome and adverse pregnancy outcomes

CM Cobb, PJ Kelly, KB Williams, S Babbar… - … journal of women's …, 2017 - Taylor & Francis
Significant evidence supports an association between periodontal pathogenic bacteria and
preterm birth and preeclampsia. The virulence properties assigned to specific oral …

Distal consequences of oral inflammation

JE Konkel, C O'Boyle, S Krishnan - Frontiers in immunology, 2019 - frontiersin.org
Periodontitis is an incredibly prevalent chronic inflammatory disease, which results in the
destruction of tooth supporting structures. However, in addition to causing tooth and alveolar …