RTS, S/AS01 vaccine (Mosquirix™): an overview
MB Laurens - Human vaccines & immunotherapeutics, 2020 - Taylor & Francis
Malaria is an illness caused by Plasmodium parasites transmitted to humans by infected
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
mosquitoes. Of the five species that infect humans, P. falciparum exacts the highest toll in …
Malaria eradication within a generation: ambitious, achievable, and necessary
Executive summary 50 years after a noble but flawed attempt to eradicate malaria in the mid-
20th century, the global malaria community is once again seriously considering eradication …
20th century, the global malaria community is once again seriously considering eradication …
Low-dose subcutaneous or intravenous monoclonal antibody to prevent malaria
RL Wu, AH Idris, NM Berkowitz, M Happe… - … England Journal of …, 2022 - Mass Medical Soc
Background New approaches for the prevention and elimination of malaria, a leading cause
of illness and death among infants and young children globally, are needed. Methods We …
of illness and death among infants and young children globally, are needed. Methods We …
Malaria vaccines: recent advances and new horizons
The development of highly effective and durable vaccines against the human malaria
parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor …
parasites Plasmodium falciparum and P. vivax remains a key priority. Decades of endeavor …
Malaria vaccines since 2000: progress, priorities, products
PE Duffy, J Patrick Gorres - npj Vaccines, 2020 - nature.com
Malaria vaccine development entered a new era in 2015 when the pre-erythrocytic
Plasmodium falciparum candidate RTS, S was favorably reviewed by the European …
Plasmodium falciparum candidate RTS, S was favorably reviewed by the European …
Advances and opportunities in malaria population genomics
Almost 20 years have passed since the first reference genome assemblies were published
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
for Plasmodium falciparum, the deadliest malaria parasite, and Anopheles gambiae, the …
malERA: an updated research agenda for malaria elimination and eradication
Achieving a malaria-free world presents exciting scientific challenges as well as
overwhelming health, equity, and economic benefits. WHO and countries are setting …
overwhelming health, equity, and economic benefits. WHO and countries are setting …
Attenuated PfSPZ Vaccine induces strain-transcending T cells and durable protection against heterologous controlled human malaria infection
KE Lyke, AS Ishizuka, AA Berry… - Proceedings of the …, 2017 - National Acad Sciences
A live-attenuated malaria vaccine, Plasmodium falciparum sporozoite vaccine (PfSPZ
Vaccine), confers sterile protection against controlled human malaria infection (CHMI) with …
Vaccine), confers sterile protection against controlled human malaria infection (CHMI) with …
Mapping functional humoral correlates of protection against malaria challenge following RTS, S/AS01 vaccination
TJ Suscovich, JK Fallon, J Das, AR Demas… - Science translational …, 2020 - science.org
Vaccine development has the potential to be accelerated by coupling tools such as systems
immunology analyses and controlled human infection models to define the protective …
immunology analyses and controlled human infection models to define the protective …
[HTML][HTML] Protection against Plasmodium falciparum malaria by PfSPZ Vaccine
JE Epstein, KM Paolino, TL Richie, M Sedegah… - JCI insight, 2017 - ncbi.nlm.nih.gov
BACKGROUND: A radiation-attenuated Plasmodium falciparum (Pf) sporozoite (SPZ)
malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf …
malaria vaccine, PfSPZ Vaccine, protected 6 of 6 subjects (100%) against homologous Pf …