Mutations in mitochondrial DNA (mtDNA) contribute to multiple diseases. However, how new
mtDNA mutations arise and accumulate with age remains understudied because of the high …

Perfluorooctanoic acid (PFOA) is a persistent environmental pollutant that can impair
ovarian function, while the underlying mechanism is not fully understood, and effective …

The rate of infertility continues to rise in the world for several reasons, including the age of
conception and current lifestyle. We list in this paper potential non-invasive and invasive …

Female reproduction focuses mainly on achieving fully grown follicles and competent
oocytes to be successfully fertilized, as well as on nourishing the developing offspring once …

The follicle is the functional unit of the ovary, whereby ovarian development is largely
dependent on the development of the follicles themselves. The activation, growth, and …

Rotenone, an insecticide that inhibits mitochondrial complex I and generates oxidative
stress, is responsible for neurological disorders and affects the female reproductive system …

The in vitro maturation efficiency of porcine oocytes is relatively low, and this limits the
production of in vitro porcine embryos. Since melatonin is involved in mammalian …

Objectives Per‐and polyfluoroalkyl substances (PFAS) are man‐made chemicals that are
widely used in various products. PFAS are characterized by their fluorinated carbon chains …

Arsenic (AS), an environmental contaminant, is a known human carcinogen that can cause
cancer of the lung, liver, and skin. Furthermore, AS induces oxidative stress and …

Maternal ageing is one of the major causes of reduced ovarian reserve and low oocyte
quality in elderly women. Decreased oocyte quality is the main cause of age‐related …