Iron Absorption: Molecular and Pathophysiological Aspects

M Correnti, E Gammella, G Cairo, S Recalcati - Metabolites, 2024 - mdpi.com
Iron is an essential nutrient for growth among all branches of life, but while iron is among the
most common elements, bioavailable iron is a relatively scarce nutrient. Since iron is …

Progress in the detection of erythropoietin in blood, urine, and tissue

Y Yasuoka, Y Izumi, JM Sands, K Kawahara… - Molecules, 2023 - mdpi.com
Detection of erythropoietin (Epo) was difficult until a method was developed by the World
Anti-Doping Agency (WADA). WADA recommended the Western blot technique using …

Disproportionality analysis on hypothyroidism with roxadustat using the Japanese adverse drug event database

Y Kouki, N Okada, K Saga, M Ozaki… - The Journal of …, 2023 - Wiley Online Library
Hypoxia‐inducible factor prolyl‐hydroxylase inhibitor (HIF‐PHI) is a novel agent for the
treatment of renal anemia. HIF‐PHI increases endogenous erythropoietin production by …

[HTML][HTML] Iron chelators as mitophagy agents: Potential and limitations

T Brogyanyi, Z Kejík, K Veselá, P Dytrych… - Biomedicine & …, 2024 - Elsevier
Mitochondrial autophagy (mitophagy) is very important process for the maintenance of
cellular homeostasis, functionality and survival. Its dysregulation is associated with high risk …

Hepcidin and erythroferrone response to 3 weeks of exposure to normobaric hypoxia at rest in trained cyclists

K Płoszczyca, M Czuba, M Chalimoniuk… - Frontiers in …, 2023 - frontiersin.org
Purpose: The effectiveness of altitude training on haematological adaptations is largely
dependent on iron metabolism. Hepcidin and erythroferrone (ERFE) are key iron-regulating …

Anemia of Chronic Kidney Disease—A Narrative Review of Its Pathophysiology, Diagnosis, and Management

K Badura, J Janc, J Wąsik, S Gnitecki, S Skwira… - Biomedicines, 2024 - mdpi.com
Anemia is one of the most common chronic kidney disease (CKD) complications. It
negatively affects patients' quality of life and clinical outcomes. The pathophysiology of …

Minerals and the Menstrual Cycle: Impacts on Ovulation and Endometrial Health

C Kapper, P Oppelt, C Ganhör, AA Gyunesh… - Nutrients, 2024 - mdpi.com
The role of minerals in female fertility, particularly in relation to the menstrual cycle, presents
a complex area of study that underscores the interplay between nutrition and reproductive …

[HTML][HTML] Hypoxia Pathways in Parkinson's Disease: From Pathogenesis to Therapeutic Targets

Y Gao, J Zhang, T Tang, Z Liu - International Journal of Molecular …, 2024 - mdpi.com
The human brain is highly dependent on oxygen, utilizing approximately 20% of the body's
oxygen at rest. Oxygen deprivation to the brain can lead to loss of consciousness within …

Tubular Endogenous Erythropoietin Protects Renal Function against Ischemic Reperfusion Injury

Y Yasuoka, Y Izumi, T Fukuyama, T Oshima… - International Journal of …, 2024 - mdpi.com
Many large-scale studies show that exogenous erythropoietin, erythropoiesis-stimulating
agents, lack any renoprotective effects. We investigated the effects of endogenous …

Iron and cardiovascular health: A review

D Othon-Martínez… - Journal of …, 2024 - journals.sagepub.com
Iron is an essential element for the biological processes of living organisms, including the
production of crucial oxygen-carrying proteins, formation of heme enzymes, and playing …