Cryo-electron tomography and subtomogram averaging are rising and fast-evolving imaging
techniques to study biological events, providing structural information at an unprecedented …

Traditionally, the field of genomics has been studied from a biochemical perspective.
Besides chemical influences, cells are subject to a variety of mechanical signals from their …

Recent technological advances have deepened our perception of cellular structure.
However, most structural data doesn't originate from intact cells, limiting our understanding …

Cellular and developmental biology spans a huge portion of modern biology, so providing a
brief synopsis of a decade of progress is a particularly daunting task. Collectively our …

Biological function of macromolecules is closely tied to their cellular location, as well as to
interactions with other molecules within the native environment of the cell. Therefore, to …

FlowDenoising is a software tool that implements an adaptive Gaussian denoising filter that
preserves visually appreciable structures in volumes of 3D electron microscopy (3DEM). It …

Imaging technologies have played a pivotal role in advancing biological research by
enabling visualization of biological structures and processes. While traditional electron …

Fluorescence microscopy has witnessed many clever innovations in the last two decades,
leading to new methods such as structured illumination and super-resolution microscopies …

Cryo-electron microscopy (cryo-EM) has revolutionized our understanding of
macromolecular complexes, enabling high-resolution structure determination. With the …

Cryo-electron microscopy was developed as a powerful tool for imaging biological
specimens in near-native conditions. Nowadays, advances in technology, equipment and …