Cryoelectron microscopy (cryo-EM) has revolutionized the structural determination of
macromolecular complexes. With the paradigm shift to structure determination of highly …

Focused ion beam (FIB) techniques are employed widely for nanofabrication and
processing of materials and devices. However, ion irradiation often gives rise to severe …

Recent technological advances have deepened our perception of cellular structure.
However, most structural data doesn't originate from intact cells, limiting our understanding …

Traditionally, the field of genomics has been studied from a biochemical perspective.
Besides chemical influences, cells are subject to a variety of mechanical signals from their …

Cellular and developmental biology spans a huge portion of modern biology, so providing a
brief synopsis of a decade of progress is a particularly daunting task. Collectively our …

Fluorescence microscopy has witnessed many clever innovations in the last two decades,
leading to new methods such as structured illumination and super-resolution microscopies …

Three-dimensional electron tomography was employed to carry out a thorough and
quantitative analysis of the porosity in biomass tobacco and its resulting carbon materials …

The objective of this work is to highlight the power of isotope-edited Fourier transform
infrared (FTIR) spectroscopy in resolving important problems encountered in biochemistry …

Cryo-electron microscopy was developed as a powerful tool for imaging biological
specimens in near-native conditions. Nowadays, advances in technology, equipment and …

Cryo-focused ion beam milling has enabled groundbreaking structural discoveries in native
cells. Progress toward medically relevant applications, however, has been slow. We here …