The cardiovascular system provides blood supply throughout the body and as such is
perpetually applying mechanical forces to cells and tissues. Thus, this system is primed with …

Piezo1 is an essential mechanosensitive transduction ion channel in mammals. Its unique
structure makes it capable of converting mechanical cues into electrical and biological …

Glomerular podocyte injury plays an essential role in proteinuria pathogenesis, a hallmark of
chronic kidney disease, including hypertensive nephropathy. Although podocytes are …

Background Vasculopathy is the most common complication of diabetes. Endothelial cells
located in the innermost layer of blood vessels are constantly affected by blood flow or …

Chronic kidney disease affects≈ 15% of US adults or 37 million people, resulting in $87
billion health care cost annually. 1 Diabetes, obesity, and hypertension are leading risk …