New Mechanisms to Prevent Heart Failure with Preserved Ejection Fraction Using Glucagon-like Peptide-1 Receptor Agonism (GLP-1 RA) in Metabolic Syndrome and …
This review examines the impact of obesity on the pathophysiology of heart failure with
preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF …
preserved ejection fraction (HFpEF) and focuses on novel mechanisms for HFpEF …
ICAM-1 on the luminal surface of endothelial cells is induced to a greater extent in mouse retina than in other tissues in diabetes
Aims/hypothesis Induction of intercellular adhesion molecule-1 (ICAM-1) has been
implicated in the development of macrovascular and microvascular diseases such as …
implicated in the development of macrovascular and microvascular diseases such as …
[HTML][HTML] Association between insulin resistance and serum insulin-like growth factor 1 levels in patients with non-remitting major depressive disorder
H Arinami, Y Suzuki, Y Watanabe, M Tajiri… - Journal of Affective …, 2024 - Elsevier
Background Major depressive disorder (MDD) is linked to an increased risk of diabetes;
however, the underlying pathomechanism remains unknown. Although insulin-like growth …
however, the underlying pathomechanism remains unknown. Although insulin-like growth …
KD025 is a casein kinase 2 inhibitor that protects against glucolipotoxicity in beta cells
R Devkota, JC Small, K Carbone, MA Glass… - Diabetes, 2024 - Am Diabetes Assoc
Glucolipotoxicity (GLT), in which elevated levels of glucose and fatty acids have deleterious
effects on β-cell biology, is thought to be one of the major contributors in progression of type …
effects on β-cell biology, is thought to be one of the major contributors in progression of type …
Sevoflurane and isoflurane inhibit KCl-induced, Rho kinase-mediated, and PI3K-participated vasoconstriction in aged diabetic rat aortas
S Yang, Y Liu, S Huang, F Jin, F Qi - BMC anesthesiology, 2021 - Springer
Background The mechanism of volatile anesthetics on vascular smooth muscle (VSM)
contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was …
contraction in the setting of diabetes mellitus (DM) remains unclear. The current study was …
[HTML][HTML] Involvement of the hippo pathway in the development of diabetes
Y Wang, H Yu, J He - Discovery Medicine, 2021 - discoverymedicine.com
The Hippo pathway is a complex signaling network that plays an important role in regulating
cellular and metabolic tissue processes, as well as in controlling organ size. However …
cellular and metabolic tissue processes, as well as in controlling organ size. However …
[PDF][PDF] Biomarkers, Pandemics and Host Response Treatment
D Fedson - J Nur Healthcare, 2024 - opastpublishers.com
Biomarkers for the COVID-19 pandemic and other forms of severe critical illness are
beneficially affected by generic drugs–statins, ACE inhibitors, angiotensin receptor blockers …
beneficially affected by generic drugs–statins, ACE inhibitors, angiotensin receptor blockers …
Speckle-Tracking Echocardiography is Preferable Measurement for Detecting the Early and Subtle Alterations of Cardiac Dysfunction in Diabetic Rats
Z Chen, Y Qi, L Wang, M Ma, N Li, Z Liu, S Liu, L Xue… - 2021 - researchsquare.com
Background Myocardial damage caused by diabetic cardiomyopathy results in cardiac
structural and functional abnormalities. Our previous studies have demonstrated that …
structural and functional abnormalities. Our previous studies have demonstrated that …