Epidemiologic studies have previously suggested that premenopausal females have
reduced incidence of cardiovascular disease (CVD) when compared to age-matched males …

Estrogens mediate profound effects throughout the body and regulate physiological and
pathological processes in both women and men. The low prevalence of many diseases in …

Estrogen is a potent steroid with pleiotropic effects, which have yet to be fully elucidated.
Estrogen has both nuclear and non-nuclear effects. The rapid response to estrogen, which …

Estrogen has pleiotropic effects on the cardiovascular system. The mechanisms by which
estrogen confers these pleiotropic effects are undergoing active investigation. Until a …

Ethnopharmacological relevance Cinnamomum cassia is a well-known traditional Chinese
herb that is widely used for the treatment of ischemic heart disease (IHD). It has favorable …

Skeletal muscle mass, strength, and regenerative capacity decline with age, with many
measures showing a greater deterioration in females around the time estrogen levels …

In this review, we aim to provide an overview of the recent advances in understanding
estrogen effects on the vascular endothelium. Epidemiological studies suggest the female …

The number of people diagnosed with neurodegenerative diseases is on the rise. Many of
these diseases, including Alzheimer's disease, Parkinson's disease, multiple sclerosis, and …

Endogenous estrogens are important regulators of cardiovascular homeostasis in
premenopausal women and delay the development of hypertension and coronary artery …

GPER possesses structural and functional characteristics shared by members of the G-
protein-coupled receptor (GPCR) superfamily, the largest class of plasma membrane …